Human Anterior gradient-2 protein (Recombinant) (STJP001863)
SPECIFICATIONS
HostHEK293
ConjugationUnconjugated
ImmunogenOptimized DNA sequence encoding mature chain of human anterior gradient-2, AGR2 (ARG21-LEU175 ) , including a C-terminal His tag was expressed in HEK293 cells. NA
General Information
| Short Description | Recombinant-Human Anterior gradient-2-protein was developed from hek293. For use in research applications. |
| Host | HEK293 |
| Note | STRICTLY FOR FURTHER RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Conjugation | Unconjugated |
| Dilution Range | Spin the vial and reconstite in distilled water to a concentration not less than 0.1 mg/mL. This can then be diluted into other buffers. |
| Formulation | Lyophilised from 0.2 Mu m filtered PBS solution, pH7.2, 5% Trehalose. |
| Storage Instruction | Can be stored in working aliquots at 2°C-8°C C for one month, or at-20°C to-70°C for 1 year. Avoid repeated freeze/thaw cycles. NA |
| Endotoxin | Endotoxin content was assayed using a LAL gel clot method. Endotoxin level was found to be less than 0.1 ng/µg (1EU/µg). NA |
Target Information
| Gene Symbol | AGR2 |
| Gene ID | 10551 |
| Uniprot ID | AGR2_HUMAN |
| Immunogen | Optimized DNA sequence encoding mature chain of human anterior gradient-2, AGR2 (ARG21-LEU175 ) , including a C-terminal His tag was expressed in HEK293 cells. NA |
| Immunogen Region | ARG21-LEU175 |
Additional Info
| Tissue Specificity | Expressed strongly in trachea, lung, stomach, colon, prostate and small intestine. Expressed weakly in pituitary gland, salivary gland, mammary gland, bladder, appendix, ovary, fetal lung, uterus, pancreas, kidney, fetal kidney, testis, placenta, thyroid gland and in estrogen receptor (ER)-positive breast cancer cell lines. |
| Function | Required for MUC2 post-transcriptional synthesis and secretion. May play a role in the production of mucus by intestinal cells. Proto-oncogene that may play a role in cell migration, cell differentiation and cell growth. Promotes cell adhesion. |
| Protein Name | Anterior Gradient Protein 2 HomologAg-2Hag-2Hpc8Secreted Cement Gland Protein Xag-2 Homolog |
| Database Links | |
| Cellular Localisation | SecretedEndoplasmic Reticulum |
| Alternative Protein Names | Anterior Gradient Protein 2 Homolog proteinAg-2 proteinHag-2 proteinHpc8 proteinSecreted Cement Gland Protein Xag-2 Homolog proteinAGR2 proteinAG2 proteinUNQ515 proteinPRO1030 protein |
Information sourced from Uniprot.org