Human Annexin A5/ANXA5 protein (Recombinant) (C-His) (STJP001194)
SPECIFICATIONS
HostE.coli
ConjugationUnconjugated
ImmunogenRecombinant Human Annexin A5/ANXA5 Protein is produced by E. coli expression system. The target protein is expressed with sequence (Met1-Asp320) of human Annexin A5/Annexin V/ANXA5 (Accession #NP_001145.1) fused with a 6×His tag at the C-terminus.
General Information
| Short Description | Recombinant-Human Annexin A5/ANXA5-C-His protein was developed in e.coli using the region Met1-Asp320. For use in research applications. |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Conjugation | Unconjugated |
| Formulation | Lyophilised from a 0.22 Mu m filtered solution of PBS, pH 7.4. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Immunoreactivity | Measured by its binding ability in a functional ELISA. Immobilized Human Annexin A5 at 10 Mu g/mL (100 Mu L/well) can bind Human GSTO1 with a linear range of 0.15-3.16 Mu g/mL. |
| Determination Method | < 1.0 EU/Mu g of the protein by LAL method. |
Target Information
| Gene Symbol | ANXA5 |
| Gene ID | 308 |
| Uniprot ID | ANXA5_HUMAN |
| Immunogen | Recombinant Human Annexin A5/ANXA5 Protein is produced by E. coli expression system. The target protein is expressed with sequence (Met1-Asp320) of human Annexin A5/Annexin V/ANXA5 (Accession #NP_001145.1) fused with a 6×His tag at the C-terminus. |
| Immunogen Region | Met1-Asp320 |
| Immunogen Sequence | MAQVLRGTVTDFPGFDERAD AETLRKAMKGLGTDEESILT LLTSRSNAQRQEISAAFKTL FGRDLLDDLKSELTGKFEKL IVALMKPSRLYDAYELKHAL KGAGTNEKVLTEIIASRTPE ELRAIKQVYEEEYGSSLEDD VVGDTSGYYQRMLVVLLQAN RDPDAGIDEAQVEQDAQALF QAGELKWGTDEEKFITIFGT RSVSHLRKVFDKYMTISGFQ IEETIDRETSGNLEQLLLA |
Additional Info
| Function | This protein is an anticoagulant protein that acts as an indirect inhibitor of the thromboplastin-specific complex, which is involved in the blood coagulation cascade. |
| Protein Name | Annexin A5Anchorin CiiAnnexin VAnnexin-5Calphobindin ICpb-IEndonexin IiLipocortin VPlacental Anticoagulant Protein 4Pp4Placental Anticoagulant Protein IPap-IThromboplastin InhibitorVascular Anticoagulant-AlphaVac-Alpha |
| Database Links | Reactome: R-HSA-114608 |
| Cellular Localisation | |
| Alternative Protein Names | Annexin A5 proteinAnchorin Cii proteinAnnexin V proteinAnnexin-5 proteinCalphobindin I proteinCpb-I proteinEndonexin Ii proteinLipocortin V proteinPlacental Anticoagulant Protein 4 proteinPp4 proteinPlacental Anticoagulant Protein I proteinPap-I proteinThromboplastin Inhibitor proteinVascular Anticoagulant-Alpha proteinVac-Alpha proteinANXA5 proteinANX5 proteinENX2 proteinPP4 protein |
Information sourced from Uniprot.org