Human Annexin A11/ANXA11 protein (Recombinant) (His-Tag) (STJP016911)

SPECIFICATIONS
HostE.coli
ImmunogenHuman
STJP016911
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General Information

Short DescriptionRecombinant-Human Annexin A11/ANXA11-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications.
ApplicationsSDS-PAGE
HostE.coli
NoteSTRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Product Properties

Concentration0.25 mg/mL
FormulationLiquid in 20mM MES buffer (pH 5.0) containing 20% Glycerol, 2mM DTT, 100mM NaCl
Storage InstructionFor short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles.

Target Information

Gene SymbolANXA11
Gene ID311
Uniprot IDANX11_HUMAN
Accession NumberNP_001148.1
ImmunogenHuman
Immunogen Region1-505aa
Immunogen Sequence MSYPGYPPPP GGYPPAAPGG GPWGGAAYPP PPSMPPIGLD NVATYAGQFN QDYLSGMAAN MSGTFGGANM PNLYPGAPGA GYPPVPPGGF GQPPSAQQPV PPYGMYPPPG GNPPSRMPSY PPYPGAPVPG QPMPPPGQQP PGAYPGQPPV TYPGQPPVPL PGQQQPVPSY PGYPGSGTVT PAVPPTQFGS RGTITDAPGF DPLRDA

Additional Info

Function Binds specifically to calcyclin in a calcium-dependent manner. Required for midbody formation and completion of the terminal phase of cytokinesis.
Protein Name Annexin A11
56 Kda Autoantigen
Annexin Xi
Annexin-11
Calcyclin-Associated Annexin 50
Cap-50
Database Links
Cellular Localisation Cytoplasm
Melanosome
Nucleus Envelope
Nucleus
Nucleoplasm
Cytoskeleton
Spindle
Found Throughout The Nucleoplasm At Interphase And During Mitosis Concentrates Around The Mitotic Apparatus
Elevation Of Intracellular Calcium Causes Relocalization From The Nucleoplasm To The Nuclear Envelope
With Little Effect On The Cytoplasmic Pool
Localization To The Nuclear Envelope Is Cell-Cycle Dependent
Alternative Protein Names Annexin A11 protein
56 Kda Autoantigen protein
Annexin Xi protein
Annexin-11 protein
Calcyclin-Associated Annexin 50 protein
Cap-50 protein
ANXA11 protein
ANX11 protein

Information sourced from Uniprot.org

Citations

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