Human ANKRD2 protein (Recombinant) (N-His) (STJP007659)
SPECIFICATIONS
HostE.coli
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human ANKRD2-N-His protein was developed from e.coli for the region N-His. For use in research applications. |
| Applications | ELISA/Immunogen/SDS-PAGE/WB |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Dilution Range | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Formulation | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
Target Information
| Gene Symbol | ANKRD2 |
| Gene ID | 26287 |
| Uniprot ID | ANKR2_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Asp148-His333 |
Additional Info
| Post Translational Modifications | Phosphorylation at Ser-99 by PKB/AKT2 in response to oxidative stress induces translocation to the nucleus and negatively regulates myoblast differentiation. |
| Function | Functions as a negative regulator of myocyte differentiation. May interact with both sarcoplasmic structural proteins and nuclear proteins to regulate gene expression during muscle development and in response to muscle stress. |
| Protein Name | Ankyrin Repeat Domain-Containing Protein 2Skeletal Muscle Ankyrin Repeat ProteinHarpp |
| Database Links | |
| Cellular Localisation | CytoplasmMyofibrilSarcomereI BandCytosolNucleusPml BodyIn The Sarcoplasm Of Differentiated Striated Muscle CellsWhere It Is Cytosolic And Enriched In The I BandIn Nucleus And Pml Bodies Of Proliferating And Undifferentiated MyoblastsAssociates With The Euchromatin In The Nucleus Of Myocytes Upon Muscle Stress |
| Alternative Protein Names | Ankyrin Repeat Domain-Containing Protein 2 proteinSkeletal Muscle Ankyrin Repeat Protein proteinHarpp proteinANKRD2 proteinARPP protein |
Information sourced from Uniprot.org