Human ANKRD1 protein (Recombinant) (His-Tag) (STJP017827)

SPECIFICATIONS
HostE.coli
ImmunogenHuman
STJP017827
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General Information

Short DescriptionRecombinant-Human ANKRD1-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications.
ApplicationsSDS-PAGE
HostE.coli
NoteSTRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Product Properties

Concentration0.25 mg/mL
FormulationLiquid in 20mM Tris-HCl buffer (pH 8.5) containing 0.2M NaCl, 50% Glycerol, 5mM DTT
Storage InstructionFor short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles.

Target Information

Gene SymbolANKRD1
Gene ID27063
Uniprot IDANKR1_HUMAN
Accession NumberNP_055206
ImmunogenHuman
Immunogen Region1-319aa
Immunogen SequenceMVLKVE ELVTGKKNGN GEAGEFLPED FRDGEYEAAV TLEKQEDLKT LLAHPVTLGE QQWKSEKQRE AELKKKKLEQ RSKLENLEDL EIIIQLKKRK KYRKTKVPVV KEPEPEIITE PVDVPTFLKA ALENKLPVVE KFLSDKNNPD VCDEYKRTAL HRACLEGHLA IVEKLMEAGA QIEFRDMLES TAIHWASRGG NLDVLK

Additional Info

Tissue Specificity Mainly expressed in activated vascular endothelial cells. To a lower extent, also expressed in hepatoma cells.
Function May play an important role in endothelial cell activation. May act as a nuclear transcription factor that negatively regulates the expression of cardiac genes. Induction seems to be correlated with apoptotic cell death in hepatoma cells.
Protein Name Ankyrin Repeat Domain-Containing Protein 1
Cardiac Ankyrin Repeat Protein
Cytokine-Inducible Gene C-193 Protein
Cytokine-Inducible Nuclear Protein
Database Links Reactome: R-HSA-1989781
Cellular Localisation Nucleus
Alternative Protein Names Ankyrin Repeat Domain-Containing Protein 1 protein
Cardiac Ankyrin Repeat Protein protein
Cytokine-Inducible Gene C-193 Protein protein
Cytokine-Inducible Nuclear Protein protein
ANKRD1 protein
C193 protein
CARP protein
HA1A2 protein

Information sourced from Uniprot.org

Citations

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