Human ANGPT4 protein (Recombinant-Active) (C-10*His) (STJP012326)
SPECIFICATIONS
HostMammalian Cells
ConjugationUnconjugated
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Active-Human ANGPT4-C-10*His protein was developed from mammalian cells and has a target region of C-10*His. For use in research applications. |
| Applications | ELISA/WB |
| Host | Mammalian Cells |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Conjugation | Unconjugated |
| Dilution Range | Reconstitute in sterile water for a stock solution. |
| Formulation | Lyophilized from a solution in PBS pH 7.4, 5% Trehalose, 5% Mannitol. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at-20 to-80°C for twelve months from the date of receipt. |
| Endotoxin | <0.1 EU/Mu g of the protein by the LAL method. |
| Immunoreactivity | Measured by its ability to compete with biotinylated rhAng-2 for binding to Immobilised Tie-2 in a functional ELISA. Compared to rmAngiopoietin-3, rhANGPT4 is less effective in this competitive assay. |
Target Information
| Gene Symbol | ANGPT4 |
| Gene ID | 51378 |
| Uniprot ID | ANGP4_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Gln24-Ile503 |
Additional Info
| Function | Binds to TEK/TIE2, modulating ANGPT1 signaling. Can induce tyrosine phosphorylation of TEK/TIE2. Promotes endothelial cell survival, migration and angiogenesis. |
| Protein Name | Angiopoietin-4Ang-4Angiopoietin-3Ang-3 |
| Database Links | Reactome: R-HSA-210993 |
| Cellular Localisation | Secreted |
| Alternative Protein Names | Angiopoietin-4 proteinAng-4 proteinAngiopoietin-3 proteinAng-3 proteinANGPT4 proteinANG3 proteinANG4 protein |
Information sourced from Uniprot.org