Human Angiopoietin-like 7/ANGPTL7 protein (Recombinant) (hIgG-Tag) (STJP019508)
SPECIFICATIONS
HostHEK293 Cells
ImmunogenHuman
General Information
| Short Description | Recombinant-Human Angiopoietin-like 7/ANGPTL7-hIgG-Tag protein was developed from hek293 cells and has a target region of hIgG-Tag. For use in research applications. |
| Applications | SDS-PAGE |
| Host | HEK293 Cells |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Concentration | 0.25 mg/mL |
| Formulation | Liquid In Phosphate-Buffered Saline (pH 7.4) containing 10% Glycerol |
| Storage Instruction | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
| Endotoxin | < 1 EU per 1ug of protein (determined by LAL method) |
Target Information
| Gene Symbol | ANGPTL7 |
| Gene ID | 10218 |
| Uniprot ID | ANGL7_HUMAN |
| Accession Number | NP_066969.1 |
| Immunogen | Human |
| Immunogen Region | 27-346aa |
| Immunogen Sequence | QKLSKHKTPA QPQLKAANCC EEVKELKAQV ANLSSLLSEL NKKQERDWVS VVMQVMELES NSKRMESRLT DAESKYSEMN NQIDIMQLQA AQTVTQTSAD AIYDCSSLYQ KNYRISGVYK LPPDDFLGSP ELEVFCDMET SGGGWTIIQR RKSGLVSFYR DWKQYKQGFG SIRGDFWLGN EHIHRLSRQP TRLRVEMEDW EGNLRYAEYS HFVLGNELNS YRLFLGNY |
Additional Info
| Tissue Specificity | Highly expressed in the cornea (at protein level). Expression is restricted to the stromal layer. Also detected at the junction between the corneal stromal layer and the conjuctiva. Not detected in the sclera. |
| Function | Has a role in the formation and organization of the extracellular matrix. In the eye, it functions as a mediator of dexamethasone-induced matrix deposition in the trabecular meshwork, the tissue responsible for the outflow of the ocular aqueous humor and for the maintenance of intraocular pressure. Is a negative regulator of angiogenesis in the cornea, and plays a major role in maintaining corneal avascularity and transparency. |
| Protein Name | Angiopoietin-Related Protein 7Angiopoietin-Like FactorAngiopoietin-Like Protein 7Cornea-Derived Transcript 6 Protein |
| Database Links | |
| Cellular Localisation | Secreted |
| Alternative Protein Names | Angiopoietin-Related Protein 7 proteinAngiopoietin-Like Factor proteinAngiopoietin-Like Protein 7 proteinCornea-Derived Transcript 6 Protein proteinANGPTL7 proteinCDT6 proteinUNQ313 proteinPRO356 protein |
Information sourced from Uniprot.org