Human ANAPC13 protein (Recombinant) (T7-Tag) (STJP017532)
SPECIFICATIONS
HostE.coli
ImmunogenHuman
General Information
| Short Description | Recombinant-Human ANAPC13-T7-Tag protein was developed from e.coli and has a target region of T7-Tag. For use in research applications. |
| Applications | SDS-PAGE |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Concentration | 1 mg/mL |
| Formulation | Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 20% Glycerol, 1mM DTT, 0.1M NaCl |
| Storage Instruction | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | ANAPC13 |
| Gene ID | 25847 |
| Uniprot ID | APC13_HUMAN |
| Accession Number | NP_056206 |
| Immunogen | Human |
| Immunogen Region | 1-74aa |
| Immunogen Sequence | MASMTGGQQM GRGSHMDSEV QRDGRILDLI DDAWREDKLP YEDVAIPLNE LPEPEQDNGG TTESVKEQEM KWTDLALQYL HENVPPIGN |
Additional Info
| Function | Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains. The APC/C complex catalyzes assembly of branched 'Lys-11'-/'Lys-48'-linked branched ubiquitin chains on target proteins. |
| Protein Name | Anaphase-Promoting Complex Subunit 13Apc13Cyclosome Subunit 13 |
| Database Links | Reactome: R-HSA-983168 |
| Cellular Localisation | Nucleus |
| Alternative Protein Names | Anaphase-Promoting Complex Subunit 13 proteinApc13 proteinCyclosome Subunit 13 proteinANAPC13 protein |
Information sourced from Uniprot.org