Human AMHR2/MISR2 protein (Recombinant) (C-6His) (STJP020097)
SPECIFICATIONS
HostHEK293 cells
ConjugationUnconjugated
ImmunogenRecombinant Human AMHR2/MISR2 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Ala17-Ser144) of Human AMHR2/MISR2 (Accession #NP_065434.1) fused with His at the C-terminus.
General Information
| Short Description | Recombinant-Human AMHR2/MISR2-C-6His protein was developed in hek293 cells using the region Ala17-Ser144. For use in research applications. |
| Host | HEK293 cells |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Conjugation | Unconjugated |
| Formulation | Lyophilised from a 0.2 Mu m filtered solution of PBS, pH 7.4. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Determination Method | < 1 EU/Mu g of the protein by LAL method. |
Target Information
| Gene Symbol | AMHR2 |
| Gene ID | 269 |
| Uniprot ID | AMHR2_HUMAN |
| Immunogen | Recombinant Human AMHR2/MISR2 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Ala17-Ser144) of Human AMHR2/MISR2 (Accession #NP_065434.1) fused with His at the C-terminus. |
| Immunogen Region | Ala17-Ser144 |
| Immunogen Sequence | APPNRRTCVFFEAPGVRGST KTLGELLDTGTELPRAIRCL YSRCCFGIWNLTQDRAQVEM QGCRDSDEPGCESLHCDPSP RAHPSPGSTLFTCSCGTDFC NANYSHLPPPGSPGTPGSQG PQAAPGES |
Additional Info
| Function | On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for anti-Muellerian hormone. |
| Protein Name | Anti-Muellerian Hormone Type-2 ReceptorAnti-Muellerian Hormone Type Ii ReceptorAmh Type Ii ReceptorMis Type Ii ReceptorMisriiMrii |
| Database Links | Reactome: R-HSA-201451 |
| Cellular Localisation | MembraneSingle-Pass Type I Membrane Protein |
| Alternative Protein Names | Anti-Muellerian Hormone Type-2 Receptor proteinAnti-Muellerian Hormone Type Ii Receptor proteinAmh Type Ii Receptor proteinMis Type Ii Receptor proteinMisrii proteinMrii proteinAMHR2 proteinAMHR proteinMISR2 protein |
Information sourced from Uniprot.org