| Short Description : | Recombinant-Human Alpha-2-MRAP/LRPAP1-C-His protein was developed in e.coli using the region Tyr35-Leu357. For use in research applications. |
| Host: | E.coli |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Conjugation: | Unconjugated |
| Formulation: | Lyophilised from a 0.22 Mu m filtered solution of 20mM Tris, 150mM NaCl, 5% Glycerol, pH 8.0. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Determination Method: | < 1.0 EU/Mu g of the protein by LAL method. |
| Gene Symbol: | LRPAP1 |
| Gene ID: | 4043 |
| Uniprot ID: | AMRP_HUMAN |
| Immunogen: | Recombinant Human Alpha-2-MRAP/LRPAP1 Protein is produced by E. coli expression system. The target protein is expressed with sequence (Tyr35-Leu357) of human LRPAP (Accession #NP_002328.1) fused with an initial Met at the N-terminus and a 6×His tag a |
| Immunogen Region: | Tyr35-Leu357 |
| Immunogen Sequence: | YSREKNQPKPSPKRESGEEF RMEKLNQLWEKAQRLHLPPV RLAELHADLKIQERDELAWK KLKLDGLDEDGEKEARLIRN LNVILAKYGLDGKKDARQVT SNSLSGTQEDGLDDPRLEKL WHKAKTSGKFSGEELDKLWR EFLHHKEKVHEYNVLLETLS RTEEIHENVISPSDLSDIKG SVLHSRHTELKEKLRSINQG LDRLRRVSHQGYSTEAEFEE PRVIDLWDLAQSANLTDKE |
| Post Translational Modifications | N-glycosylated. |
| Function | Molecular chaperone for LDL receptor-related proteins that may regulate their ligand binding activity along the secretory pathway. |
| Protein Name | Alpha-2-Macroglobulin Receptor-Associated ProteinAlpha-2-MrapLow Density Lipoprotein Receptor-Related Protein-Associated Protein 1Rap |
| Database Links | |
| Cellular Localisation | Rough Endoplasmic Reticulum LumenEndoplasmic Reticulum-Golgi Intermediate Compartment LumenGolgi ApparatusCis-Golgi NetworkGolgi Apparatus LumenEndosome LumenCell SurfaceMay Be Associated With Receptors At The Cell Surface |
| Alternative Protein Names | Alpha-2-Macroglobulin Receptor-Associated Protein proteinAlpha-2-Mrap proteinLow Density Lipoprotein Receptor-Related Protein-Associated Protein 1 proteinRap proteinLRPAP1 proteinA2MRAP protein |
Information sourced from Uniprot.org
