Name: Human ALK-7/ACVR1C protein (Recombinant) (C-hFc&His) (STJP001023)
SKU: STJP001023
Availability: InStock

Human ALK-7/ACVR1C protein (Recombinant) (C-hFc&His) (STJP001023)

SKU:

STJP001023

$108.68 - $347.63

Host:	HEK293 cells
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Formulation:	Lyophilised from a 0.22 Mu m filtered solution of PBS, pH 7.4.
Storage Instruction:	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Determination Method:	< 0.1 EU/Mu g of the protein by LAL method.

Gene Symbol:	ACVR1C
Gene ID:	130399
Uniprot ID:	ACV1C_HUMAN
Immunogen:	Recombinant Human ALK-7/ACVR1C Protein is produced by HEK293 expression system. The target protein is expressed with sequence (Leu22-Glu113) of human ALK-7 Protein (Accession #NP_660302.2) fused with an Fc, 6×His tag at the C-terminus.
Immunogen Sequence:	LSPGLKCVCLLCDSSNFTCQ TEGACWASVMLTNGKEQVIK SCVSLPELNAQVFCHSSNNV TKTECCFTDFCNNITLHLPT ASPNAPKLGPME

Function	Serine/threonine protein kinase which forms a receptor complex on ligand binding. The receptor complex consisting of 2 type II and 2 type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators, SMAD2 and SMAD3. Receptor for activin AB, activin B and NODAL. Plays a role in cell differentiation, growth arrest and apoptosis.
Protein Name	Activin Receptor Type-1c Activin Receptor Type Ic Actr-Ic Activin Receptor-Like Kinase 7 Alk-7
Database Links	Reactome: R-HSA-1181150 Reactome: R-HSA-1433617 Reactome: R-HSA-1502540
Cellular Localisation	Membrane Single-Pass Type I Membrane Protein
Alternative Protein Names	Activin Receptor Type-1c protein Activin Receptor Type Ic protein Actr-Ic protein Activin Receptor-Like Kinase 7 protein Alk-7 protein ACVR1C protein ALK7 protein

Information sourced from Uniprot.org

Model	Name	Host
STJP002553	Human ALK-4/ACVR1B protein (Recombinant) (C-hFc & his) (STJP002553)	HEK293 cells
STJP000931	Human BMPR-1A/ALK-3 protein (Recombinant) (C-hFc&His) (STJP000931)	HEK293 cells
STJP002758	Human TGFR-1/ALK-5 protein (Recombinant) (C-hFc & His) (STJP002758)	HEK293 cells
STJP001235	Human BMPR-1B/ALK-6 protein (Recombinant) (C-hFc&His) (STJP001235)	HEK293 cells
STJP000977	Human Frizzled-7/FZD7 protein (Recombinant) (C-hFc&His) (STJP000977)	HEK293 cells
STJP000960	Human EphA3 protein (Recombinant) (C-hFc&His) (STJP000960)	HEK293 cells
STJP001047	Human SECTM1 protein (Recombinant) (C-hFc&His) (STJP001047)	HEK293 cells
STJP001074	Human CD44 protein (Recombinant) (C-hFc&His) (STJP001074)	HEK293 cells
STJP001055	Human VSIG4 protein (Recombinant) (C-hFc&His) (STJP001055)	HEK293 cells

Human ALK-7/ACVR1C protein (Recombinant) (C-hFc&His) (STJP001023)