Human ALDM (Aldehyde Dehydrogenase, Mitochondrial) Sandwich ELISA Kit Ready-To-Use Kit (STJE0013434)
SPECIFICATIONS
General Information
| Short Description | This ALDM Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human tissue homogenates, cell lysates or other biological fluids.. |
| Applications | ELISA |
| Reactivity | Human |
| Sensitivity | 0.078ng/mL |
| Detection Limit | 0.312-20ng/mL |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Storage Instruction | The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time | 3 hrs |
Target Information
| Gene Symbol | ALDH2 |
| Gene ID | 217 |
| Uniprot ID | ALDH2_HUMAN |
| Immunogen Region | Ready-To-Use |
| Sample Type | tissue homogenates, cell lysates or other biological fluids. |
Additional Info
| Tissue Specificity | |
| Post Translational Modifications | In response to mitochondrial stress, the precursor protein is ubiquitinated by the SIFI complex in the cytoplasm before mitochondrial import, leading to its degradation. Within the SIFI complex, UBR4 initiates ubiquitin chain that are further elongated or branched by KCMF1. |
| Function | Required for clearance of cellular formaldehyde, a cytotoxic and carcinogenic metabolite that induces DNA damage. |
| Protein Name | Aldehyde Dehydrogenase - MitochondrialAldh Class 2Aldh-E2Aldhi |
| Database Links | Reactome: R-HSA-380612Reactome: R-HSA-445355Reactome: R-HSA-71384Reactome: R-HSA-9837999 |
| Cellular Localisation | Mitochondrion Matrix |
| Alternative ELISA Names | Aldehyde Dehydrogenase - Mitochondrial ELISA kitAldh Class 2 ELISA kitAldh-E2 ELISA kitAldhi ELISA kitALDH2 ELISA kitALDM ELISA kit |
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Information sourced from Uniprot.org