Human ALDH1A3 protein (Recombinant) (N-His) (STJP014509)
SPECIFICATIONS
HostE.coli
ConjugationUnconjugated
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human ALDH1A3-N-His protein was developed from e.coli and has a target region of N-His. For use in research applications. |
| Applications | ELISA/WB |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Conjugation | Unconjugated |
| Formulation | Supplied as a 0.22 Mu m filtered solution in 20mM Tris-HCl, 150mM NaCl, 20% Glycerol, pH 7.5. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8ยฐC for one week. Store at-20 to-80ยฐC for twelve months from the date of receipt. |
| Endotoxin | < 1 EU/ยตg as determined by LAL test. |
Target Information
| Gene Symbol | ALDH1A3 |
| Gene ID | 220 |
| Uniprot ID | AL1A3_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Met1-Pro512 |
Additional Info
| Function | Catalyzes the NAD-dependent oxidation of aldehyde substrates, such as all-trans-retinal and all-trans-13,14-dihydroretinal, to their corresponding carboxylic acids, all-trans-retinoate and all-trans-13,14-dihydroretinoate, respectively. High specificity for all-trans-retinal as substrate, can also accept acetaldehyde as substrate in vitro but with lower affinity. Required for the biosynthesis of normal levels of retinoate in the embryonic ocular and nasal regions.a critical lipid in the embryonic development of the eye and the nasal region. |
| Protein Name | Retinaldehyde Dehydrogenase 3Raldh-3Raldh3Aldehyde Dehydrogenase 6Aldehyde Dehydrogenase Family 1 Member A3Aldh1a3 |
| Database Links | Reactome: R-HSA-5365859 |
| Cellular Localisation | Cytoplasm |
| Alternative Protein Names | Retinaldehyde Dehydrogenase 3 proteinRaldh-3 proteinRaldh3 proteinAldehyde Dehydrogenase 6 proteinAldehyde Dehydrogenase Family 1 Member A3 proteinAldh1a3 proteinALDH1A3 proteinALDH6 protein |
Information sourced from Uniprot.org