Human Aldehyde Dehydrogenase 3-A1/ALDH3A1 protein (Recombinant) (His-Tag) (STJP016614)
SPECIFICATIONS
HostE.coli
ImmunogenHuman
General Information
| Short Description | Recombinant-Human Aldehyde Dehydrogenase 3-A1/ALDH3A1-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications. |
| Applications | SDS-PAGE/Enzyme Activity |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Concentration | 0.5 mg/mL |
| Formulation | Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 10% Glycerol 0.1M NaCl |
| Storage Instruction | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
| Immunoreactivity | Specific activity is > 5, 000pmol/min/ug, and is defined as the amount of enzyme that catalyze the oxidation of 1.0 pmole 4-nitrobenzaldehyde by NADP per minute at pH 9.0 at 37 °C. |
Target Information
| Gene Symbol | ALDH3A1 |
| Gene ID | 218 |
| Uniprot ID | AL3A1_HUMAN |
| Accession Number | AAH04370.1 |
| Immunogen | Human |
| Immunogen Region | 1-453aa |
| Immunogen Sequence |
Additional Info
| Tissue Specificity | High levels in stomach, esophagus and lung.low level in the liver and kidney. |
| Function | ALDHs play a major role in the detoxification of alcohol-derived acetaldehyde (Probable). They are involved in the metabolism of corticosteroids, biogenic amines, neurotransmitters, and lipid peroxidation (Probable). Oxidizes medium and long chain aldehydes into non-toxic fatty acids. Preferentially oxidizes aromatic aldehyde substrates. Comprises about 50 percent of corneal epithelial soluble proteins. May play a role in preventing corneal damage caused by ultraviolet light. |
| Protein Name | Aldehyde Dehydrogenase - Dimeric Nadp-PreferringAldhiiiAldehyde Dehydrogenase 3Aldehyde Dehydrogenase Family 3 Member A1 |
| Database Links | Reactome: R-HSA-211945 |
| Cellular Localisation | Cytoplasm |
| Alternative Protein Names | Aldehyde Dehydrogenase - Dimeric Nadp-Preferring proteinAldhiii proteinAldehyde Dehydrogenase 3 proteinAldehyde Dehydrogenase Family 3 Member A1 proteinALDH3A1 proteinALDH3 protein |
Information sourced from Uniprot.org