Human AKR1D1 protein (Recombinant) (N-His) (STJP015787)
SPECIFICATIONS
HostE.coli
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human AKR1D1-N-His protein was developed from e.coli for the region N-His. For use in research applications. |
| Applications | ELISA/Immunogen/SDS-PAGE/WB |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Dilution Range | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Formulation | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
| Endotoxin | Please contact us for further information. |
Target Information
| Gene Symbol | AKR1D1 |
| Gene ID | 6718 |
| Uniprot ID | AK1D1_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Met1-Tyr326 |
Additional Info
| Function | Catalyzes the stereospecific NADPH-dependent reduction of the C4-C5 double bond of bile acid intermediates and steroid hormones carrying a delta(4)-3-one structure to yield an A/B cis-ring junction. This cis-configuration is crucial for bile acid biosynthesis and plays important roles in steroid metabolism. Capable of reducing a broad range of delta-(4)-3-ketosteroids from C18 (such as, 17beta-hydroxyestr-4-en-3-one) to C27 (such as, 7alpha-hydroxycholest-4-en-3-one). |
| Protein Name | Aldo-Keto Reductase Family 1 Member D13-Oxo-5-Beta-Steroid 4-DehydrogenaseDelta(4-3-Ketosteroid 5-Beta-ReductaseDelta(4-3-Oxosteroid 5-Beta-Reductase |
| Database Links | Reactome: R-HSA-193368Reactome: R-HSA-193775Reactome: R-HSA-193807 |
| Cellular Localisation | Cytoplasm |
| Alternative Protein Names | Aldo-Keto Reductase Family 1 Member D1 protein3-Oxo-5-Beta-Steroid 4-Dehydrogenase proteinDelta(4-3-Ketosteroid 5-Beta-Reductase proteinDelta(4-3-Oxosteroid 5-Beta-Reductase proteinAKR1D1 proteinSRD5B1 protein |
Information sourced from Uniprot.org