Human AKAP7 protein (Recombinant) (N-His-SUMO) (STJP009579)
SPECIFICATIONS
HostE.coli
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human AKAP7-N-His-SUMO protein was developed from e.coli for the region N-His-SUMO. For use in research applications. |
| Applications | ELISA/Immunogen/SDS-PAGE/WB |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Dilution Range | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Formulation | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
Target Information
| Gene Symbol | AKAP7 |
| Gene ID | 9465 |
| Uniprot ID | AKA7A_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Ile16-Lys104 |
Additional Info
| Function | Targets the cAMP-dependent protein kinase (PKA) to the plasma membrane, and permits functional coupling to the L-type calcium channel. The membrane-associated form reduces epithelial sodium channel (ENaC) activity, whereas the free cytoplasmic form may negatively regulate ENaC channel feedback inhibition by intracellular sodium. |
| Protein Name | A-Kinase Anchor Protein 7 Isoforms Alpha And BetaAkap-7 Isoforms Alpha And BetaA-Kinase Anchor Protein 18 KdaAkap 18Protein Kinase A-Anchoring Protein 7 Isoforms Alpha/BetaPrka7 Isoforms Alpha/Beta |
| Database Links | |
| Cellular Localisation | Isoform Alpha: Lateral Cell MembraneLipid-AnchorTargeted Predominantly To The Lateral MembraneIsoform Beta: Apical Cell MembraneTargeted Predominantly To The Apical Membrane |
| Alternative Protein Names | A-Kinase Anchor Protein 7 Isoforms Alpha And Beta proteinAkap-7 Isoforms Alpha And Beta proteinA-Kinase Anchor Protein 18 Kda proteinAkap 18 proteinProtein Kinase A-Anchoring Protein 7 Isoforms Alpha/Beta proteinPrka7 Isoforms Alpha/Beta proteinAKAP7 proteinAKAP15 proteinAKAP18 protein |
Information sourced from Uniprot.org