Human AKAP7 protein (Recombinant) (His-Tag) (STJP017640)
SPECIFICATIONS
HostE.coli
ImmunogenHuman
General Information
| Short Description | Recombinant-Human AKAP7-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications. |
| Applications | SDS-PAGE |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Concentration | 1 mg/mL |
| Formulation | Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 10% Glycerol, 1mM DTT, 50mM NaCl |
| Storage Instruction | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | AKAP7 |
| Gene ID | 9465 |
| Uniprot ID | AKA7A_HUMAN |
| Accession Number | NP_004833 |
| Immunogen | Human |
| Immunogen Region | 1-81aa |
| Immunogen Sequence |
Additional Info
| Tissue Specificity | Expressed in brain, heart, lung, pancreas and skeletal muscle. |
| Function | Targets the cAMP-dependent protein kinase (PKA) to the plasma membrane, and permits functional coupling to the L-type calcium channel. The membrane-associated form reduces epithelial sodium channel (ENaC) activity, whereas the free cytoplasmic form may negatively regulate ENaC channel feedback inhibition by intracellular sodium. |
| Protein Name | A-Kinase Anchor Protein 7 Isoforms Alpha And BetaAkap-7 Isoforms Alpha And BetaA-Kinase Anchor Protein 18 KdaAkap 18Protein Kinase A-Anchoring Protein 7 Isoforms Alpha/BetaPrka7 Isoforms Alpha/Beta |
| Database Links | |
| Cellular Localisation | Isoform Alpha: Lateral Cell MembraneLipid-AnchorTargeted Predominantly To The Lateral MembraneIsoform Beta: Apical Cell MembraneTargeted Predominantly To The Apical Membrane |
| Alternative Protein Names | A-Kinase Anchor Protein 7 Isoforms Alpha And Beta proteinAkap-7 Isoforms Alpha And Beta proteinA-Kinase Anchor Protein 18 Kda proteinAkap 18 proteinProtein Kinase A-Anchoring Protein 7 Isoforms Alpha/Beta proteinPrka7 Isoforms Alpha/Beta proteinAKAP7 proteinAKAP15 proteinAKAP18 protein |
Information sourced from Uniprot.org