Human AHSA1 protein (Recombinant) (N-His) (STJP010786)
SPECIFICATIONS
HostE.coli
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human AHSA1-N-His protein was developed from e.coli for the region N-His. For use in research applications. |
| Applications | ELISA/Immunogen/SDS-PAGE/WB |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Dilution Range | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Formulation | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
Target Information
| Gene Symbol | AHSA1 |
| Gene ID | 10598 |
| Uniprot ID | AHSA1_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | His26-Ile164 |
Additional Info
| Post Translational Modifications | Phosphorylation at Tyr-223 enhances binding to chaperone HSP90AA1. |
| Function | Acts as a co-chaperone of HSP90AA1. Activates the ATPase activity of HSP90AA1 leading to increase in its chaperone activity. Competes with the inhibitory co-chaperone FNIP1 for binding to HSP90AA1, thereby providing a reciprocal regulatory mechanism for chaperoning of client proteins. Competes with the inhibitory co-chaperone TSC1 for binding to HSP90AA1, thereby providing a reciprocal regulatory mechanism for chaperoning of client proteins. |
| Protein Name | Activator Of 90 Kda Heat Shock Protein Atpase Homolog 1Aha1P38 |
| Database Links | |
| Cellular Localisation | CytoplasmCytosolEndoplasmic ReticulumMay Transiently Interact With The Endoplasmic Reticulum |
| Alternative Protein Names | Activator Of 90 Kda Heat Shock Protein Atpase Homolog 1 proteinAha1 proteinP38 proteinAHSA1 proteinC14orf3 proteinHSPC322 protein |
Information sourced from Uniprot.org