Human AGXT2 protein (Recombinant) (N-His) (STJP005955)
SPECIFICATIONS
HostE.coli
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human AGXT2-N-His protein was developed from e.coli for the region N-His. For use in research applications. |
| Applications | ELISA/Immunogen/SDS-PAGE/WB |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Dilution Range | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Formulation | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
Target Information
| Gene Symbol | AGXT2 |
| Gene ID | 64902 |
| Uniprot ID | AGT2_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Cys259-Lys514 |
Additional Info
| Function | Multifunctional aminotransferase with a broad substrate specificity. Catalyzes the conversion of glyoxylate to glycine using alanine as the amino donor. Catalyzes metabolism of not L- but the D-isomer of D-beta-aminoisobutyric acid to generate 2-methyl-3-oxopropanoate and alanine. Catalyzes the transfer of the amino group from beta-alanine to pyruvate to yield L-alanine and 3-oxopropanoate. Can metabolize NG-monomethyl-L-arginine (NMMA), asymmetric NG,NG-dimethyl-L-arginine (ADMA) and symmetric NG,N'G-dimethyl-L-arginine (SDMA). ADMA is a potent inhibitor of nitric-oxide (NO) synthase, and this activity provides mechanism through which the kidney regulates blood pressure. |
| Protein Name | Alanine--Glyoxylate Aminotransferase 2 - MitochondrialAgt 2(R-3-Amino-2-Methylpropionate--Pyruvate TransaminaseBeta-Alaat IiBeta-Alanine-Pyruvate AminotransferaseD-3-Aminoisobutyrate-Pyruvate AminotransferaseD-AibatD-Beta-Aminoisobutyrate-Pyruvate Aminotransferase |
| Database Links | Reactome: R-HSA-389661Reactome: R-HSA-73621 |
| Cellular Localisation | Mitochondrion |
| Alternative Protein Names | Alanine--Glyoxylate Aminotransferase 2 - Mitochondrial proteinAgt 2 protein(R-3-Amino-2-Methylpropionate--Pyruvate Transaminase proteinBeta-Alaat Ii proteinBeta-Alanine-Pyruvate Aminotransferase proteinD-3-Aminoisobutyrate-Pyruvate Aminotransferase proteinD-Aibat proteinD-Beta-Aminoisobutyrate-Pyruvate Aminotransferase proteinAGXT2 proteinAGT2 protein |
Information sourced from Uniprot.org