Human AFAP1 protein (Recombinant) (N-His) (STJP009669)
SPECIFICATIONS
HostE.coli
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human AFAP1-N-His protein was developed from e.coli for the region N-His. For use in research applications. |
| Applications | ELISA/Immunogen/SDS-PAGE/WB |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Dilution Range | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Formulation | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
Target Information
| Gene Symbol | AFAP1 |
| Gene ID | 60312 |
| Uniprot ID | AFAP1_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Glu346-Ile478 |
Additional Info
| Post Translational Modifications | Phosphorylated on tyrosine residues by SRC. |
| Function | Can cross-link actin filaments into both network and bundle structures. May modulate changes in actin filament integrity and induce lamellipodia formation. May function as an adapter molecule that links other proteins, such as SRC and PKC to the actin cytoskeleton. Seems to play a role in the development and progression of prostate adenocarcinoma by regulating cell-matrix adhesions and migration in the cancer cells. |
| Protein Name | Actin Filament-Associated Protein 1110 Kda Actin Filament-Associated ProteinAfap-110 |
| Database Links | |
| Cellular Localisation | CytoplasmCytoskeletonStress Fiber |
| Alternative Protein Names | Actin Filament-Associated Protein 1 protein110 Kda Actin Filament-Associated Protein proteinAfap-110 proteinAFAP1 proteinAFAP protein |
Information sourced from Uniprot.org