Human ADIPOR1 protein (Recombinant) (N-His) (STJP006320)

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STJP006320
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human ADIPOR1-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: ADIPOR1
Gene ID: 51094
Uniprot ID: PAQR1_HUMAN
Immunogen Region: Met1-Gly136
Immunogen: Homo sapiens (Human)
Function Receptor for ADIPOQ, an essential hormone secreted by adipocytes that regulates glucose and lipid metabolism. Required for normal glucose and fat homeostasis and for maintaining a normal body weight. ADIPOQ-binding activates a signaling cascade that leads to increased AMPK activity, and ultimately to increased fatty acid oxidation, increased glucose uptake and decreased gluconeogenesis. Has high affinity for globular adiponectin and low affinity for full-length adiponectin.
Protein Name Adiponectin Receptor Protein 1
Progestin And Adipoq Receptor Family Member 1
Progestin And Adipoq Receptor Family Member I
Database Links Reactome: R-HSA-163680
Cellular Localisation Cell Membrane
Multi-Pass Membrane Protein
Localized To The Cell Membrane And Intracellular Organelles
Alternative Protein Names Adiponectin Receptor Protein 1 protein
Progestin And Adipoq Receptor Family Member 1 protein
Progestin And Adipoq Receptor Family Member I protein
ADIPOR1 protein
PAQR1 protein
TESBP1A protein
CGI-45 protein

Information sourced from Uniprot.org