Human ADH7 protein (Recombinant) (C-His) (STJP013329)
SPECIFICATIONS
HostMammalian Cells
ConjugationUnconjugated
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human ADH7-C-His protein was developed from mammalian cells and has a target region of C-His. For use in research applications. |
| Applications | ELISA/WB |
| Host | Mammalian Cells |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Conjugation | Unconjugated |
| Dilution Range | Reconstitute in sterile water for a stock solution. |
| Formulation | Lyophilized from a 0.22 Mu m filtered solution in PBS, pH 7.4. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at-20 to-80°C for twelve months from the date of receipt. |
| Endotoxin | < 1 EU/µg as determined by LAL test. |
Target Information
| Gene Symbol | ADH7 |
| Gene ID | 131 |
| Uniprot ID | ADH7_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Met1-Phe386 |
Additional Info
| Function | Catalyzes the NAD-dependent oxidation of all-trans-retinol, alcohol, and omega-hydroxy fatty acids and their derivatives. Oxidizes preferentially all trans-retinol, all-trans-4-hydroxyretinol, 9-cis-retinol, 2-hexenol, and long chain omega-hydroxy fatty acids such as juniperic acid. In vitro can also catalyze the NADH-dependent reduction of all-trans-retinal and aldehydes and their derivatives. Reduces preferentially all trans-retinal, all-trans-4-oxoretinal and hexanal. Catalyzes in the oxidative direction with higher efficiency. Therefore may participate in retinoid metabolism, fatty acid omega-oxidation, and elimination of cytotoxic aldehydes produced by lipid peroxidation. |
| Protein Name | All-Trans-Retinol Dehydrogenase Nad(+ Adh7Alcohol Dehydrogenase Class 4 Mu/Sigma ChainAlcohol Dehydrogenase Class Iv Mu/Sigma ChainGastric Alcohol DehydrogenaseOmega-Hydroxydecanoate Dehydrogenase Adh7Retinol Dehydrogenase |
| Database Links | Reactome: R-HSA-71384 |
| Cellular Localisation | Cytoplasm |
| Alternative Protein Names | All-Trans-Retinol Dehydrogenase Nad(+ Adh7 proteinAlcohol Dehydrogenase Class 4 Mu/Sigma Chain proteinAlcohol Dehydrogenase Class Iv Mu/Sigma Chain proteinGastric Alcohol Dehydrogenase proteinOmega-Hydroxydecanoate Dehydrogenase Adh7 proteinRetinol Dehydrogenase proteinADH7 protein |
Information sourced from Uniprot.org