Human ADCY5 (Adenylate Cyclase 5) Sandwich ELISA Kit (STJE0006914)
SPECIFICATIONS
General Information
| Short Description | This ADCY5 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human tissue homogenates, cell lysates or other biological fluids.. |
| Applications | ELISA |
| Reactivity | Human |
| Sensitivity | 0.124ng/mL |
| Detection Limit | 0.312-20ng/mL |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Storage Instruction | Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time | 4.5 hrs |
Target Information
| Gene Symbol | ADCY5 |
| Gene ID | 111 |
| Uniprot ID | ADCY5_HUMAN |
| Sample Type | tissue homogenates, cell lysates or other biological fluids. |
Additional Info
| Tissue Specificity | Detected in pancreas islets (at protein level). Expressed in the brain, with high expression in the corpus striatum. |
| Post Translational Modifications | Phosphorylated by RAF1. |
| Function | Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. Mediates signaling downstream of ADRB1. Regulates the increase of free cytosolic Ca(2+) in response to increased blood glucose levels and contributes to the regulation of Ca(2+)-dependent insulin secretion. |
| Protein Name | Adenylate Cyclase Type 5Atp Pyrophosphate-Lyase 5Adenylate Cyclase Type VAdenylyl Cyclase 5Ac5 |
| Database Links | Reactome: R-HSA-163359Reactome: R-HSA-163615Reactome: R-HSA-164378Reactome: R-HSA-170660Reactome: R-HSA-170670Reactome: R-HSA-381676Reactome: R-HSA-400042Reactome: R-HSA-418555Reactome: R-HSA-418594Reactome: R-HSA-418597Reactome: R-HSA-432040Reactome: R-HSA-5610787Reactome: R-HSA-9634597Reactome: R-HSA-9660821Reactome: R-HSA-9664323Reactome: R-HSA-9856530 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane ProteinCell ProjectionCilium |
| Alternative ELISA Names | Adenylate Cyclase Type 5 ELISA kitAtp Pyrophosphate-Lyase 5 ELISA kitAdenylate Cyclase Type V ELISA kitAdenylyl Cyclase 5 ELISA kitAc5 ELISA kitADCY5 ELISA kit |
| output |
Information sourced from Uniprot.org