Human ADAM8 protein (Recombinant) (STJP000576)
SPECIFICATIONS
HostHEK293
ConjugationUnconjugated
ImmunogenOptimized DNA sequence encoding extracellular domain of human Disintegrin and metalloproteinase 8 (ILE17-LEU665) including a C-terminal His tag was expressed in HEK293 cells. NA
General Information
| Short Description | Recombinant-Human ADAM8-protein was developed from hek293. For use in research applications. |
| Host | HEK293 |
| Note | STRICTLY FOR FURTHER RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Conjugation | Unconjugated |
| Dilution Range | Spin the vial and reconstite in distilled water to a concentration not less than 0.1 mg/mL. This can then be diluted into other buffers. |
| Formulation | Lyophilised from 0.2 Mu m filtered PBS solution, pH7.2, 5% Trehalose. |
| Storage Instruction | Can be stored in working aliquots at 2°C-8°C C for one month, or at-20°C to-70°C for 1 year. Avoid repeated freeze/thaw cycles. NA |
| Endotoxin | Endotoxin content was assayed using a LAL gel clot method. Endotoxin level was found to be less than 0.1 ng/µg (1EU/µg). NA |
Target Information
| Gene Symbol | ADAM8 |
| Gene ID | 101 |
| Uniprot ID | ADAM8_HUMAN |
| Immunogen | Optimized DNA sequence encoding extracellular domain of human Disintegrin and metalloproteinase 8 (ILE17-LEU665) including a C-terminal His tag was expressed in HEK293 cells. NA |
| Immunogen Region | ILE17-LEU665 |
Additional Info
| Tissue Specificity | Expressed on neutrophils and monocytes. |
| Function | Possible involvement in extravasation of leukocytes. |
| Protein Name | Disintegrin And Metalloproteinase Domain-Containing Protein 8Adam 8Cell Surface Antigen Ms2Cd Antigen Cd156a |
| Database Links | Reactome: R-HSA-1474228Reactome: R-HSA-6798695 |
| Cellular Localisation | MembraneSingle-Pass Type I Membrane Protein |
| Alternative Protein Names | Disintegrin And Metalloproteinase Domain-Containing Protein 8 proteinAdam 8 proteinCell Surface Antigen Ms2 proteinCd Antigen Cd156a proteinADAM8 proteinMS2 protein |
Information sourced from Uniprot.org