Human ADAM28 protein (Recombinant-Active) (C-His) (STJP012316)
SPECIFICATIONS
HostMammalian Cells
ConjugationUnconjugated
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Active-Human ADAM28-C-His protein was developed from mammalian cells and has a target region of C-His. For use in research applications. |
| Applications | ELISA/WB |
| Host | Mammalian Cells |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Conjugation | Unconjugated |
| Dilution Range | Reconstitute in sterile water for a stock solution. |
| Formulation | Lyophilized from a solution in PBS pH 7.4, 5% Trehalose, 5% Mannitol. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at-20 to-80°C for twelve months from the date of receipt. |
| Endotoxin | <0.1 EU/Mu g of the protein by the LAL method. |
| Immunoreactivity | Measured by its ability of the Immobilised protein to support the adhesion of human acute T cell leukemia cells (Jurkat). The ED50 for this effect is 0.250-2.50 Mu g/mL. |
Target Information
| Gene Symbol | ADAM28 |
| Gene ID | 10863 |
| Uniprot ID | ADA28_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Leu72-Ala623 |
Additional Info
| Post Translational Modifications | Pro-domain removal and maturation may be, at least in part, autocatalytic. |
| Function | May play a role in the adhesive and proteolytic events that occur during lymphocyte emigration or may function in ectodomain shedding of lymphocyte surface target proteins, such as FASL and CD40L. May be involved in sperm maturation. |
| Protein Name | Disintegrin And Metalloproteinase Domain-Containing Protein 28Adam 28Epididymal Metalloproteinase-Like - Disintegrin-Like - And Cysteine-Rich Protein IiEmdc IiMetalloproteinase-Like - Disintegrin-Like - And Cysteine-Rich Protein LMdc-L |
| Database Links | |
| Cellular Localisation | Isoform 1: Cell MembraneSingle-Pass Type I Membrane ProteinIsoform 2: Secreted |
| Alternative Protein Names | Disintegrin And Metalloproteinase Domain-Containing Protein 28 proteinAdam 28 proteinEpididymal Metalloproteinase-Like - Disintegrin-Like - And Cysteine-Rich Protein Ii proteinEmdc Ii proteinMetalloproteinase-Like - Disintegrin-Like - And Cysteine-Rich Protein L proteinMdc-L proteinADAM28 proteinADAM23 proteinMDCL protein |
Information sourced from Uniprot.org