Human ADAM12 protein (Recombinant) (N-His) (STJP003258)
SPECIFICATIONS
HostE.coli
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human ADAM12-N-His protein was developed from e.coli for the region N-His. For use in research applications. |
| Applications | ELISA/Immunogen/SDS-PAGE/WB |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Dilution Range | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Formulation | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
Target Information
| Gene Symbol | ADAM12 |
| Gene ID | 8038 |
| Uniprot ID | ADA12_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Val31-His350 |
Additional Info
| Post Translational Modifications | The precursor is cleaved by a furin endopeptidase. |
| Function | Involved in skeletal muscle regeneration, specifically at the onset of cell fusion. Also involved in macrophage-derived giant cells (MGC) and osteoclast formation from mononuclear precursors. |
| Protein Name | Disintegrin And Metalloproteinase Domain-Containing Protein 12Adam 12Meltrin-Alpha |
| Database Links | Reactome: R-HSA-177929Reactome: R-HSA-8941237 |
| Cellular Localisation | Isoform 1: Cell MembraneSingle-Pass Type I Membrane ProteinIsoform 2: SecretedIsoform 3: SecretedIsoform 4: Secreted |
| Alternative Protein Names | Disintegrin And Metalloproteinase Domain-Containing Protein 12 proteinAdam 12 proteinMeltrin-Alpha proteinADAM12 proteinMLTN proteinUNQ346 proteinPRO545 protein |
Information sourced from Uniprot.org