Human ADAM12 (ADAM12) Antibody Pair (STJAP00967)
General Information
| Short Description | This ADAM12 antibody pair contains complimentary capture and detection antibodies, which work together under the principals of the Sandwich ELISA. |
| Applications | ELISA |
| Host | Sheep/Rabbit |
| Reactivity | Human |
| Note | FOR SCIENTIFIC EDUCATIONAL RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR OTHER MEDICAL APPLICATIONS. |
Product Properties
| Conjugation | Unconjugated/Biotin |
| Concentration | 0.5 mg/mL/0.5-4ug/mL |
| Dilution Range | 1:1000-1:10000 |
| Storage Instruction | Store at-20°C for the long term, and avoid freeze-thaw cycles. |
| Detection | Colorimetric method;ELISA;Sandwich |
Target Information
| Gene Symbol | ADAM12 |
| Gene ID | 8038 |
| Uniprot ID | ADA12_HUMAN |
| Sample Type | Serum, plasma and other biological fluids |
Additional Info
| Post Translational Modifications | The precursor is cleaved by a furin endopeptidase. |
| Function | Involved in skeletal muscle regeneration, specifically at the onset of cell fusion. Also involved in macrophage-derived giant cells (MGC) and osteoclast formation from mononuclear precursors. |
| Protein Name | Disintegrin And Metalloproteinase Domain-Containing Protein 12Adam 12Meltrin-Alpha |
| Database Links | Reactome: R-HSA-177929Reactome: R-HSA-8941237 |
| Cellular Localisation | Isoform 1: Cell MembraneSingle-Pass Type I Membrane ProteinIsoform 2: SecretedIsoform 3: SecretedIsoform 4: Secreted |
| Alternative Antibody Pair Names | Disintegrin And Metalloproteinase Domain-Containing Protein 12 antibody pairAdam 12 antibody pairMeltrin-Alpha antibody pairADAM12 antibody pairMLTN antibody pairUNQ346 antibody pairPRO545 antibody pair |
Information sourced from Uniprot.org
Citations
Product Review
Frequently Asked Questions
Common questions about Human ADAM12 (ADAM12) Antibody Pair (STJAP00967)
This antibody pair is designed to detect human ADAM12 (UniProt O43184) and has confirmed reactivity against human samples only.
The pair consists of a sheep-raised capture antibody supplied unconjugated at 0.5 mg/mL, and a rabbit-raised detection antibody supplied biotinylated at 0.5 to 4 ug/mL.
This antibody pair is validated for use in sandwich ELISA with colorimetric detection. No other assay formats are listed for this product.
Validated sample types include serum, plasma, and other biological fluids. This product is for research use only and is not intended for diagnostic or therapeutic applications.
A working dilution range of 1:1000 to 1:10000 is specified for this antibody pair, though users should optimize conditions empirically for their specific experimental setup.
Both components should be stored at -20 degrees Celsius for long-term storage. Repeated freeze-thaw cycles should be avoided to preserve antibody integrity.
Orders typically arrive within 1 to 2 weeks, and often sooner depending on your location. If your timeline is critical, please contact us before ordering and we can advise on current lead times.
This product is shipped on gel ice packs to maintain integrity during transit. Priority shipping is used as standard to minimise time in transit.
A Certificate of Analysis (CoA) is provided with every order. If you do not receive one, please contact us and we will issue it promptly.