Human ACVR1C protein (Recombinant) (N-His) (STJP005721)

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STJP005721
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human ACVR1C-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: ACVR1C
Gene ID: 130399
Uniprot ID: ACV1C_HUMAN
Immunogen Region: Glu21-Ala493
Immunogen: Homo sapiens (Human)
Function Serine/threonine protein kinase which forms a receptor complex on ligand binding. The receptor complex consisting of 2 type II and 2 type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators, SMAD2 and SMAD3. Receptor for activin AB, activin B and NODAL. Plays a role in cell differentiation, growth arrest and apoptosis.
Protein Name Activin Receptor Type-1c
Activin Receptor Type Ic
Actr-Ic
Activin Receptor-Like Kinase 7
Alk-7
Database Links Reactome: R-HSA-1181150
Reactome: R-HSA-1433617
Reactome: R-HSA-1502540
Cellular Localisation Membrane
Single-Pass Type I Membrane Protein
Alternative Protein Names Activin Receptor Type-1c protein
Activin Receptor Type Ic protein
Actr-Ic protein
Activin Receptor-Like Kinase 7 protein
Alk-7 protein
ACVR1C protein
ALK7 protein

Information sourced from Uniprot.org

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