Human ACTN2 protein (Recombinant) (N-His) (STJP007614)
SPECIFICATIONS
HostE.coli
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human ACTN2-N-His protein was developed from e.coli for the region N-His. For use in research applications. |
| Applications | ELISA/Immunogen/SDS-PAGE/WB |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Dilution Range | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Formulation | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
Target Information
| Gene Symbol | ACTN2 |
| Gene ID | 88 |
| Uniprot ID | ACTN2_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Lys509-Leu894 |
Additional Info
| Post Translational Modifications | Ubiquitinated by FBXL22, leading to proteasomal degradation. |
| Function | F-actin cross-linking protein which is thought to anchor actin to a variety of intracellular structures. This is a bundling protein. |
| Protein Name | Alpha-Actinin-2Alpha-Actinin Skeletal Muscle Isoform 2F-Actin Cross-Linking Protein |
| Database Links | Reactome: R-HSA-114608Reactome: R-HSA-373753Reactome: R-HSA-390522Reactome: R-HSA-438066Reactome: R-HSA-442982Reactome: R-HSA-5673001Reactome: R-HSA-9609736Reactome: R-HSA-9617324Reactome: R-HSA-9620244 |
| Cellular Localisation | CytoplasmMyofibrilSarcomereZ LineColocalizes With Myoz1 And Flnc At The Z-Lines Of Skeletal Muscle |
| Alternative Protein Names | Alpha-Actinin-2 proteinAlpha-Actinin Skeletal Muscle Isoform 2 proteinF-Actin Cross-Linking Protein proteinACTN2 protein |
Information sourced from Uniprot.org