Human ACBP/DBI protein (Recombinant) (His-Tag) (STJP016707)

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STJP016707
£125.50 - £649.50
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Host: E.coli
Applications: SDS-PAGE
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human ACBP/DBI-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications.
Formulation: Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 0.1M NaCl, 10% Glycerol
Concentration: 1 mg/mL
Storage Instruction: For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles.
Gene Symbol: DBI
Gene ID: 1622
Uniprot ID: ACBP_HUMAN
Immunogen Region: 1-87aa
Accession Number: NP_001073331
Immunogen: Human
Immunogen Sequence: MSQAEFEKAA EEVRHLKTKP SDEEMLFIYG HYKQATVGDI NTERPGMLDF TGKAKWDAWN ELKGTSKEDA MKAYINKVEE LKKKYGI
Tissue Specificity Isoform 1 is ubiquitous, with a moderate expression level. Isoform 2 is ubiquitous with high level in liver and adipose tissue. Isoform 3 is ubiquitous with strong expression in adipose tissue and heart.
Function Binds medium- and long-chain acyl-CoA esters with very high affinity and may function as an intracellular carrier of acyl-CoA esters. It is also able to displace diazepam from the benzodiazepine (BZD) recognition site located on the GABA type A receptor. It is therefore possible that this protein also acts as a neuropeptide to modulate the action of the GABA receptor.
Protein Name Acyl-Coa-Binding Protein
Acbp
Diazepam-Binding Inhibitor
Dbi
Endozepine
Ep
Database Links Reactome: R-HSA-77289
Cellular Localisation Endoplasmic Reticulum
Golgi Apparatus
Golgi Localization Is Dependent On Ligand Binding
Alternative Protein Names Acyl-Coa-Binding Protein protein
Acbp protein
Diazepam-Binding Inhibitor protein
Dbi protein
Endozepine protein
Ep protein
DBI protein

Information sourced from Uniprot.org

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