Human ACBP/DBI protein (Recombinant) (His-Tag) (STJP016707)
SPECIFICATIONS
HostE.coli
ImmunogenHuman
General Information
| Short Description | Recombinant-Human ACBP/DBI-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications. |
| Applications | SDS-PAGE |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Concentration | 1 mg/mL |
| Formulation | Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 0.1M NaCl, 10% Glycerol |
| Storage Instruction | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | DBI |
| Gene ID | 1622 |
| Uniprot ID | ACBP_HUMAN |
| Accession Number | NP_001073331 |
| Immunogen | Human |
| Immunogen Region | 1-87aa |
| Immunogen Sequence |
Additional Info
| Tissue Specificity | Isoform 1 is ubiquitous, with a moderate expression level. Isoform 2 is ubiquitous with high level in liver and adipose tissue. Isoform 3 is ubiquitous with strong expression in adipose tissue and heart. |
| Function | Binds medium- and long-chain acyl-CoA esters with very high affinity and may function as an intracellular carrier of acyl-CoA esters. It is also able to displace diazepam from the benzodiazepine (BZD) recognition site located on the GABA type A receptor. It is therefore possible that this protein also acts as a neuropeptide to modulate the action of the GABA receptor. |
| Protein Name | Acyl-Coa-Binding ProteinAcbpDiazepam-Binding InhibitorDbiEndozepineEp |
| Database Links | Reactome: R-HSA-77289 |
| Cellular Localisation | Endoplasmic ReticulumGolgi ApparatusGolgi Localization Is Dependent On Ligand Binding |
| Alternative Protein Names | Acyl-Coa-Binding Protein proteinAcbp proteinDiazepam-Binding Inhibitor proteinDbi proteinEndozepine proteinEp proteinDBI protein |
Information sourced from Uniprot.org