Human ACADSB protein (Recombinant) (N-His) (STJP008026)

SPECIFICATIONS
HostE.coli
ImmunogenHomo sapiens (Human)
STJP008026
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General Information

Short DescriptionRecombinant-Human ACADSB-N-His protein was developed from e.coli for the region N-His. For use in research applications.
ApplicationsELISA/Immunogen/SDS-PAGE/WB
HostE.coli
NoteSTRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Product Properties

Dilution RangeReconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
FormulationLyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage InstructionUse a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.

Target Information

Gene SymbolACADSB
Gene ID36
Uniprot IDACDSB_HUMAN
ImmunogenHomo sapiens (Human)
Immunogen RegionThr58-Tyr432

Additional Info

Function Short and branched chain specific acyl-CoA dehydrogenase that catalyzes the removal of one hydrogen from C-2 and C-3 of the fatty acyl-CoA thioester, resulting in the formation of trans-2-enoyl-CoA. Among the different mitochondrial acyl-CoA dehydrogenases, acts specifically on short and branched chain acyl-CoA derivatives such as (S)-2-methylbutyryl-CoA as well as short straight chain acyl-CoAs such as butyryl-CoA. Plays an important role in the metabolism of L-isoleucine by catalyzing the dehydrogenation of 2-methylbutyryl-CoA, one of the steps of the L-isoleucine catabolic pathway. Can also act on valproyl-CoA, a metabolite of valproic acid, an antiepileptic drug.
Protein Name Short/Branched Chain Specific Acyl-Coa Dehydrogenase - Mitochondrial
Sbcad
2-Methyl Branched Chain Acyl-Coa Dehydrogenase
2-Mebcad
2-Methylbutyryl-Coenzyme A Dehydrogenase
2-Methylbutyryl-Coa Dehydrogenase
Database Links Reactome: R-HSA-70895
Reactome: R-HSA-9837999
Cellular Localisation Mitochondrion Matrix
Alternative Protein Names Short/Branched Chain Specific Acyl-Coa Dehydrogenase - Mitochondrial protein
Sbcad protein
2-Methyl Branched Chain Acyl-Coa Dehydrogenase protein
2-Mebcad protein
2-Methylbutyryl-Coenzyme A Dehydrogenase protein
2-Methylbutyryl-Coa Dehydrogenase protein
ACADSB protein

Information sourced from Uniprot.org

Citations

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