Human ACADSB protein (Recombinant) (His-Tag) (STJP017737)
SPECIFICATIONS
HostE.coli
ImmunogenHuman
General Information
| Short Description | Recombinant-Human ACADSB-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications. |
| Applications | SDS-PAGE |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Concentration | 0.5 mg/mL |
| Formulation | Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 0.1M NaCl, 10% Glycerol, 1mM DTT |
| Storage Instruction | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | ACADSB |
| Gene ID | 36 |
| Uniprot ID | ACDSB_HUMAN |
| Accession Number | NP_001600 |
| Immunogen | Human |
| Immunogen Region | 34-432aa |
| Immunogen Sequence |
Additional Info
| Tissue Specificity | Ubiquitously expressed. |
| Function | Short and branched chain specific acyl-CoA dehydrogenase that catalyzes the removal of one hydrogen from C-2 and C-3 of the fatty acyl-CoA thioester, resulting in the formation of trans-2-enoyl-CoA. Among the different mitochondrial acyl-CoA dehydrogenases, acts specifically on short and branched chain acyl-CoA derivatives such as (S)-2-methylbutyryl-CoA as well as short straight chain acyl-CoAs such as butyryl-CoA. Plays an important role in the metabolism of L-isoleucine by catalyzing the dehydrogenation of 2-methylbutyryl-CoA, one of the steps of the L-isoleucine catabolic pathway. Can also act on valproyl-CoA, a metabolite of valproic acid, an antiepileptic drug. |
| Protein Name | Short/Branched Chain Specific Acyl-Coa Dehydrogenase - MitochondrialSbcad2-Methyl Branched Chain Acyl-Coa Dehydrogenase2-Mebcad2-Methylbutyryl-Coenzyme A Dehydrogenase2-Methylbutyryl-Coa Dehydrogenase |
| Database Links | Reactome: R-HSA-70895Reactome: R-HSA-9837999 |
| Cellular Localisation | Mitochondrion Matrix |
| Alternative Protein Names | Short/Branched Chain Specific Acyl-Coa Dehydrogenase - Mitochondrial proteinSbcad protein2-Methyl Branched Chain Acyl-Coa Dehydrogenase protein2-Mebcad protein2-Methylbutyryl-Coenzyme A Dehydrogenase protein2-Methylbutyryl-Coa Dehydrogenase proteinACADSB protein |
Information sourced from Uniprot.org