Human ACAD8 protein (Recombinant) (His-Tag) (STJP018521)
SPECIFICATIONS
HostE.coli
ImmunogenHuman
General Information
| Short Description | Recombinant-Human ACAD8-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications. |
| Applications | SDS-PAGE |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Concentration | 0.25 mg/mL |
| Formulation | Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 30% Glycerol, 1mM DTT |
| Storage Instruction | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | ACAD8 |
| Gene ID | 27034 |
| Uniprot ID | ACAD8_HUMAN |
| Accession Number | NP_055199 |
| Immunogen | Human |
| Immunogen Region | 23-415aa |
| Immunogen Sequence | MGSSHHHHHH SSGLVPRGSH MGSLVQTGHR SLTSCIDPSM GLNEEQKEFQ KVAFDFAARE MAPNMAEWDQ KELFPVDVMR KAAQLGFGGV YIQTDVGGSG LSRLDTSVIF EALATGCTST TAYISIHNMC AWMIDSFGNE EQRHKFCPPL CTMEKFASYC LTEPGSGSDA ASLLTSAKKQ GDHYILNGSK AFISGAGESD IYVVMCRTGG PGPKGISCIV VEKGTPGL |
Additional Info
| Tissue Specificity | Detected at comparable levels in heart, lung, brain, skeletal muscle, pancreas and placenta. Weakly expressed in liver and kidney. |
| Function | Isobutyryl-CoA dehydrogenase which catalyzes the conversion of 2-methylpropanoyl-CoA to (2E)-2-methylpropenoyl-CoA in the valine catabolic pathway. To a lesser extent, also able to catalyze the oxidation of (2S)-2-methylbutanoyl-CoA. |
| Protein Name | Isobutyryl-Coa Dehydrogenase - MitochondrialIbdhActivator-Recruited Cofactor 42 Kda ComponentArc42Acyl-Coa Dehydrogenase Family Member 8Acad-8 |
| Database Links | Reactome: R-HSA-70895Reactome: R-HSA-9837999 |
| Cellular Localisation | Mitochondrion |
| Alternative Protein Names | Isobutyryl-Coa Dehydrogenase - Mitochondrial proteinIbdh proteinActivator-Recruited Cofactor 42 Kda Component proteinArc42 proteinAcyl-Coa Dehydrogenase Family Member 8 proteinAcad-8 proteinACAD8 proteinARC42 proteinIBD protein |
Information sourced from Uniprot.org