Human ACACa (Acetyl Coenzyme A Carboxylase Alpha) Sandwich ELISA Kit Ready-To-Use Kit (STJE0013208)
SPECIFICATIONS
General Information
| Short Description | This ACACa Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human serum, plasma or other biological fluids.. |
| Applications | ELISA |
| Reactivity | Human |
| Sensitivity | 1.09ng/mL |
| Detection Limit | 3.12-200ng/mL |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Storage Instruction | The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time | 3 hrs |
Target Information
| Gene Symbol | ACACA |
| Gene ID | 31 |
| Uniprot ID | ACACA_HUMAN |
| Immunogen Region | Ready-To-Use |
| Sample Type | serum, plasma or other biological fluids. |
Additional Info
| Tissue Specificity | Expressed in brain, placenta, skeletal muscle, renal, pancreatic and adipose tissues.expressed at low level in pulmonary tissue.not detected in the liver. |
| Post Translational Modifications | Phosphorylation on Ser-1263 is required for interaction with BRCA1. Phosphorylation at Ser-80 by AMPK inactivates enzyme activity. The biotin cofactor is covalently attached to the central biotinyl-binding domain and is required for the catalytic activity. |
| Function | Cytosolic enzyme that catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the first and rate-limiting step of de novo fatty acid biosynthesis. This is a 2 steps reaction starting with the ATP-dependent carboxylation of the biotin carried by the biotin carboxyl carrier (BCC) domain followed by the transfer of the carboxyl group from carboxylated biotin to acetyl-CoA. |
| Protein Name | Acetyl-Coa Carboxylase 1Acc1Acetyl-Coenzyme A Carboxylase AlphaAcc-Alpha |
| Database Links | Reactome: R-HSA-163765Reactome: R-HSA-196780Reactome: R-HSA-200425Reactome: R-HSA-2426168Reactome: R-HSA-3371599Reactome: R-HSA-75105 |
| Cellular Localisation | CytoplasmCytosol |
| Alternative ELISA Names | Acetyl-Coa Carboxylase 1 ELISA kitAcc1 ELISA kitAcetyl-Coenzyme A Carboxylase Alpha ELISA kitAcc-Alpha ELISA kitACACA ELISA kitACAC ELISA kitACC1 ELISA kitACCA ELISA kit |
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Information sourced from Uniprot.org