Human ABP1/AOC1 protein (Recombinant) (His-Tag) (STJP019432)

Name: Human ABP1/AOC1 protein (Recombinant) (His-Tag) (STJP019432)
SKU: STJP019432
Availability: InStock

⇓ Datasheet ⇓ SDS

SPECIFICATIONS

HostHEK293 Cells

ImmunogenHuman

STJP019432

Current Stock:

🚚 Free UK Delivery on orders over £150

Quantity:

Processing The item has been added

Enquire For Bulk Order

✓ 1-Year Performance Guarantee | SDS & Datasheet Included | Expert Tech Support | Covered by St John's Laboratory Guarantee

Short Description	Recombinant-Human ABP1/AOC1-His-Tag protein was developed from hek293 cells and has a target region of His-Tag. For use in research applications.
Applications	SDS-PAGE
Host	HEK293 Cells
Note	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Concentration	0.25 mg/mL
Formulation	Liquid in phosphate-Buffered Saline (pH 7.4) containing 10% Glycerol
Storage Instruction	For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles.
Endotoxin	< 1 EU per 1ug of protein (determined by LAL method)

Gene Symbol	AOC1
Gene ID	26
Uniprot ID	AOC1_HUMAN
Accession Number	NP_001082
Immunogen	Human
Immunogen Region	20-751aa
Immunogen Sequence	EPSPGTLPRK AGVFSDLSNQ ELKAVHSFLW SKKELRLQPS STTTMAKNTV FLIEMLLPKK YHVLRFLDKG ERHPVREARA VIFFGDQEHP NVTEFAVGPL PGPCYMRALS PRPGYQSSWA SRPISTAEYA LLYHTLQEAT KPLHQFFLNT TGFSFQDCHD RCLAFTDVAP RGVASGQRRS WLIIQRYVEG YFLHPTGLEL LVDHGSTDAG HWAVEQVWYN GKFYGSPE

Tissue Specificity	Widely expressed with higher expression in placenta and kidney.
Post Translational Modifications	N-glycosylated. Topaquinone (TPQ) is generated by copper-dependent autoxidation of a specific tyrosyl residue.
Function	Catalyzes the oxidative deamination of primary amines to the corresponding aldehydes with the concomitant production of hydrogen peroxide and ammonia. Its preferred substrates are the diamines histamine and 1-methylhistamine and it could therefore play a role in allergic and immune responses. Has a broad specificity for diamines and can also act on cadaverine and putrescine, two products of amino acid catabolism. It could also act on polyamines, like spermidine and spermine though less efficiently, and regulate various biological processes.
Protein Name	Diamine Oxidase Copper-Containing Diamine Oxidase Amiloride-Binding Protein Amiloride-Binding Protein 1 Amine Oxidase Copper Domain-Containing Protein 1 Histaminase Kidney Amine Oxidase Kao Kdao
Database Links	Reactome: R-HSA-211945 Reactome: R-HSA-6798695
Cellular Localisation	Secreted Extracellular Space Cell Membrane Peripheral Membrane Protein Extracellular Side
Alternative Protein Names	Diamine Oxidase Copper-Containing protein Diamine Oxidase protein Amiloride-Binding Protein protein Amiloride-Binding Protein 1 protein Amine Oxidase Copper Domain-Containing Protein 1 protein Histaminase protein Kidney Amine Oxidase protein Kao protein Kdao protein AOC1 protein ABP protein ABP1 protein DAO protein

Information sourced from Uniprot.org