Human ABO protein (Recombinant) (His-Tag) (STJP017313)
SPECIFICATIONS
HostE.coli
ImmunogenHuman
General Information
| Short Description | Recombinant-Human ABO-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications. |
| Applications | SDS-PAGE |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Concentration | 0.5 mg/mL |
| Formulation | Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 2mM DTT, 20% Glycerol, 200mM NaCl |
| Storage Instruction | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | ABO |
| Gene ID | 28 |
| Uniprot ID | BGAT_HUMAN |
| Accession Number | NP_065202 |
| Immunogen | Human |
| Immunogen Region | 54-354aa |
| Immunogen Sequence | MGSSHHHHHH SSGLVPRGSH MAVREPDHLQ RVSLPRMVYP QPKVLTPCRK DVLVVTPWLA PIVWEGTFNI DILNEQFRLQ NTTIGLTVFA IKKYVAFLKL FLETAEKHFM VGHRVHYYVF TDQPAAVPRV TLGTGRQLSV LEVRAYKRWQ DVSMRRMEMI SDFCERRFLS EVDYLVCVDV DMEFRDHVGV EILTPLFGTL HPGFYGSSRE AFTYERRPQS QAYIPKDE |
Additional Info
| Tissue Specificity | Expressed at high levels in testis. Also expressed in pancreas, uterus and lung and salivary gland. |
| Post Translational Modifications | The soluble form derives from the membrane form by proteolytic processing. |
| Function | This protein is the basis of the ABO blood group system. The histo-blood group ABO involves three carbohydrate antigens: A, B, and H. A, B, and AB individuals express a glycosyltransferase activity that converts the H antigen to the A antigen (by addition of UDP-GalNAc) or to the B antigen (by addition of UDP-Gal), whereas O individuals lack such activity. Glycosyltransferase that catalyzes the transfer of carbohydrates to H antigen, forming the antigenic structures of the ABO blood group. |
| Protein Name | Histo-Blood Group Abo System TransferaseFucosylglycoprotein 3-Alpha-GalactosyltransferaseFucosylglycoprotein Alpha-N-AcetylgalactosaminyltransferaseGlycoprotein-Fucosylgalactoside Alpha-N-AcetylgalactosaminyltransferaseGlycoprotein-Fucosylgalactoside Alpha-GalactosyltransferaseHisto-Blood Group A TransferaseA TransferaseHisto-Blood Group B TransferaseB TransferaseNagat Cleaved Into - Fucosylglycoprotein Alpha-N-Acetylgalactosaminyltransferase Soluble Form |
| Database Links | Reactome: R-HSA-9033807 |
| Cellular Localisation | Golgi ApparatusGolgi Stack MembraneSingle-Pass Type Ii Membrane ProteinSecretedMembrane-Bound Form In Trans Cisternae Of GolgiSecreted Into The Body Fluid |
| Alternative Protein Names | Histo-Blood Group Abo System Transferase proteinFucosylglycoprotein 3-Alpha-Galactosyltransferase proteinFucosylglycoprotein Alpha-N-Acetylgalactosaminyltransferase proteinGlycoprotein-Fucosylgalactoside Alpha-N-Acetylgalactosaminyltransferase proteinGlycoprotein-Fucosylgalactoside Alpha-Galactosyltransferase proteinHisto-Blood Group A Transferase proteinA Transferase proteinHisto-Blood Group B Transferase proteinB Transferase proteinNagat Cleaved Into - Fucosylglycoprotein Alpha-N-Acetylgalactosaminyltransferase Soluble Form proteinABO protein |
Information sourced from Uniprot.org