Human ABHD14B protein (Recombinant) (His-Tag) (STJP017517)

Name: Human ABHD14B protein (Recombinant) (His-Tag) (STJP017517)
SKU: STJP017517
Availability: InStock

⇓ Datasheet ⇓ SDS

SPECIFICATIONS

HostE.coli

ImmunogenHuman

STJP017517

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Short Description	Recombinant-Human ABHD14B-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications.
Applications	SDS-PAGE
Host	E.coli
Note	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Concentration	0.5 mg/mL
Formulation	Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 10% Glycerol, 100mM NaCl
Storage Instruction	For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles.

Gene Symbol	ABHD14B
Gene ID	84836
Uniprot ID	ABHEB_HUMAN
Accession Number	NP_116139
Immunogen	Human
Immunogen Region	1-210aa
Immunogen Sequence	MAASVE QREGTIQVQG QALFFREALP GSGQARFSVL LLHGIRFSSE TWQNLGTLHR LAQAGYRAVA IDLPGLGHSK EAAAPAPIGE LAPGSFLAAV VDALELGPPV VISPSLSGMY SLPFLTAPGS QLPGFVPVAP ICTDKINAAN YASVKTPALI VYGDQDPMGQ TSFEHLKQLP NHRVLIMKGA GHPCYLDKPE EWHTGL

Tissue Specificity	Ubiquitous. Detected in spleen, thymus, prostate, testis, ovary, small intestine, colon, peripheral blood leukocyte, heart, placenta, lung, liver, skeletal muscle, pancreas and kidney.
Function	Acts as an atypical protein-lysine deacetylase in vitro. Catalyzes the deacetylation of lysine residues using CoA as substrate, generating acetyl-CoA and the free amine of protein-lysine residues. Additional experiments are however required to confirm the protein-lysine deacetylase activity in vivo (Probable). Has hydrolase activity towards various surrogate p-nitrophenyl (pNp) substrates, such as pNp-butyrate, pNp-acetate and pNp-octanoate in vitro, with a strong preference for pNp-acetate. May activate transcription.
Protein Name	Putative Protein-Lysine Deacylase Abhd14b Alpha/Beta Hydrolase Domain-Containing Protein 14b Abhydrolase Domain-Containing Protein 14b Ccg1-Interacting Factor B
Database Links	Reactome: R-HSA-156584
Cellular Localisation	Cytoplasm Nucleus Predominantly Cytoplasmic
Alternative Protein Names	Putative Protein-Lysine Deacylase Abhd14b protein Alpha/Beta Hydrolase Domain-Containing Protein 14b protein Abhydrolase Domain-Containing Protein 14b protein Ccg1-Interacting Factor B protein ABHD14B protein CIB protein

Information sourced from Uniprot.org