Human ABHD10 protein (Recombinant) (His-Tag) (STJP017652)
SPECIFICATIONS
HostE.coli
ImmunogenHuman
General Information
| Short Description | Recombinant-Human ABHD10-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications. |
| Applications | SDS-PAGE |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Concentration | 1 mg/mL |
| Formulation | Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 20% Glycerol, 0.1M NaCl, 1mM DTT |
| Storage Instruction | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | ABHD10 |
| Gene ID | 55347 |
| Uniprot ID | ABHDA_HUMAN |
| Accession Number | NP_060864.1 |
| Immunogen | Human |
| Immunogen Region | 53-306aa |
| Immunogen Sequence |
Additional Info
| Function | Acts as an acyl-protein thioesterase that hydrolyzes fatty acids from acylated residues in proteins. Regulates the mitochondrial S-depalmitoylation of the nucleophilic active site residue of peroxiredoxin-5/PRDX5, a key antioxidant protein, therefore modulating mitochondrial antioxidant ability. Also catalyzes the deglucuronidation of mycophenolic acid acyl-glucuronide, an active metabolite of the immunosuppressant drug mycophenolate. |
| Protein Name | Palmitoyl-Protein Thioesterase Abhd10 - MitochondrialAcyl-Protein Thioesterase Abhd10Alpha/Beta Hydrolase Domain-Containing Protein 10Abhydrolase Domain-Containing Protein 10Mycophenolic Acid Acyl-Glucuronide Esterase - Mitochondrial |
| Database Links | Reactome: R-HSA-156588 |
| Cellular Localisation | Mitochondrion |
| Alternative Protein Names | Palmitoyl-Protein Thioesterase Abhd10 - Mitochondrial proteinAcyl-Protein Thioesterase Abhd10 proteinAlpha/Beta Hydrolase Domain-Containing Protein 10 proteinAbhydrolase Domain-Containing Protein 10 proteinMycophenolic Acid Acyl-Glucuronide Esterase - Mitochondrial proteinABHD10 protein |
Information sourced from Uniprot.org