Human ABCC8 (ATP Binding Cassette Transporter C8) Sandwich ELISA Kit (STJE0006826)
SPECIFICATIONS
General Information
| Short Description | This ABCC8 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human tissue homogenates, cell lysates or other biological fluids.. |
| Applications | ELISA |
| Reactivity | Human |
| Sensitivity | 0.128ng/mL |
| Detection Limit | 0.312-20ng/mL |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Storage Instruction | Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time | 4.5 hrs |
Target Information
| Gene Symbol | ABCC8 |
| Gene ID | 6833 |
| Uniprot ID | ABCC8_HUMAN |
| Sample Type | tissue homogenates, cell lysates or other biological fluids. |
Additional Info
| Tissue Specificity | |
| Post Translational Modifications | |
| Function | Regulator subunit of pancreatic ATP-sensitive potassium channel (KATP), playing a major role in the regulation of insulin release. In pancreatic cells, it forms KATP channels with KCNJ11.KCNJ11 forms the channel pore while ABCC8 is required for activation and regulation. |
| Protein Name | Atp-Binding Cassette Sub-Family C Member 8Sulfonylurea Receptor 1 |
| Database Links | Reactome: R-HSA-1296025Reactome: R-HSA-422356Reactome: R-HSA-5683177 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative ELISA Names | Atp-Binding Cassette Sub-Family C Member 8 ELISA kitSulfonylurea Receptor 1 ELISA kitABCC8 ELISA kitHRINS ELISA kitSUR ELISA kitSUR1 ELISA kit |
| output |
Information sourced from Uniprot.org