Human ABCB10 protein (Recombinant) (N-His) (STJP006079)
SPECIFICATIONS
HostE.coli
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human ABCB10-N-His protein was developed from e.coli for the region N-His. For use in research applications. |
| Applications | ELISA/Immunogen/SDS-PAGE/WB |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Dilution Range | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Formulation | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
Target Information
| Gene Symbol | ABCB10 |
| Gene ID | 23456 |
| Uniprot ID | ABCBA_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Leu492-Ala738 |
Additional Info
| Function | ATP-dependent transporter located in the mitochondrial inner membrane that catalyzes the export of biliverdin from the mitochondrial matrix, and plays a crucial role in hemoglobin synthesis and antioxidative stress. Participates in the early step of the heme biosynthetic process during insertion of iron into protoporphyrin IX (PPIX). Involved in the stabilization of the iron transporter mitoferrin-1/SLC25A37. In addition may be involved in mitochondrial unfolded protein response (UPRmt) signaling pathway, although ABCB10 probably does not participate in peptide export from mitochondria. |
| Protein Name | Atp-Binding Cassette Sub-Family B Member 10 - MitochondrialAbc-Mitochondrial Erythroid ProteinAbc-Me ProteinAtp-Binding Cassette Transporter 10Abc Transporter 10 ProteinMitochondrial Atp-Binding Cassette 2M-Abc2 |
| Database Links | Reactome: R-HSA-1369007 |
| Cellular Localisation | Mitochondrion Inner MembraneMulti-Pass Membrane Protein |
| Alternative Protein Names | Atp-Binding Cassette Sub-Family B Member 10 - Mitochondrial proteinAbc-Mitochondrial Erythroid Protein proteinAbc-Me Protein proteinAtp-Binding Cassette Transporter 10 proteinAbc Transporter 10 Protein proteinMitochondrial Atp-Binding Cassette 2 proteinM-Abc2 proteinABCB10 protein |
Information sourced from Uniprot.org