Human AANAT protein (Recombinant) (N-His) (STJP005494)
SPECIFICATIONS
HostE.coli
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human AANAT-N-His protein was developed from e.coli for the region N-His. For use in research applications. |
| Applications | ELISA/Immunogen/SDS-PAGE/WB |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Dilution Range | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Formulation | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
Target Information
| Gene Symbol | AANAT |
| Gene ID | 15 |
| Uniprot ID | SNAT_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Met1-Cys207 |
Additional Info
| Post Translational Modifications | cAMP-dependent phosphorylation on both N-terminal Thr-31 and C-terminal Ser-205 regulates AANAT activity by promoting interaction with 14-3-3 proteins. |
| Function | Controls the night/day rhythm of melatonin production in the pineal gland. Catalyzes the N-acetylation of serotonin into N-acetylserotonin, the penultimate step in the synthesis of melatonin. |
| Protein Name | Serotonin N-AcetyltransferaseSerotonin AcetylaseAralkylamine N-AcetyltransferaseAa-Nat |
| Database Links | Reactome: R-HSA-209931 |
| Cellular Localisation | Cytoplasm |
| Alternative Protein Names | Serotonin N-Acetyltransferase proteinSerotonin Acetylase proteinAralkylamine N-Acetyltransferase proteinAa-Nat proteinAANAT proteinSNAT protein |
Information sourced from Uniprot.org