Human AANAT (Arylalkylamine-N-Acetyltransferase) Sandwich ELISA Kit (STJE0006803)
SPECIFICATIONS
General Information
| Short Description | This AANAT Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human tissue homogenates, cell lysates or other biological fluids.. |
| Applications | ELISA |
| Reactivity | Human |
| Sensitivity | 0.6U/mL |
| Detection Limit | 1.56-100U/mL |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Storage Instruction | Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time | 4.5 hrs |
Target Information
| Gene Symbol | AANAT |
| Gene ID | 15 |
| Uniprot ID | SNAT_HUMAN |
| Sample Type | tissue homogenates, cell lysates or other biological fluids. |
Additional Info
| Tissue Specificity | Highly expressed in pineal gland and at lower levels in the retina. Weak expression in several brain regions and in the pituitary gland. |
| Post Translational Modifications | cAMP-dependent phosphorylation on both N-terminal Thr-31 and C-terminal Ser-205 regulates AANAT activity by promoting interaction with 14-3-3 proteins. |
| Function | Controls the night/day rhythm of melatonin production in the pineal gland. Catalyzes the N-acetylation of serotonin into N-acetylserotonin, the penultimate step in the synthesis of melatonin. |
| Protein Name | Serotonin N-AcetyltransferaseSerotonin AcetylaseAralkylamine N-AcetyltransferaseAa-Nat |
| Database Links | Reactome: R-HSA-209931 |
| Cellular Localisation | Cytoplasm |
| Alternative ELISA Names | Serotonin N-Acetyltransferase ELISA kitSerotonin Acetylase ELISA kitAralkylamine N-Acetyltransferase ELISA kitAa-Nat ELISA kitAANAT ELISA kitSNAT ELISA kit |
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Information sourced from Uniprot.org