• Biotinylated Human 4-1BB on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.
  • The purity of Biotinylated Human 4-1BB is greater than 95% as determined by SEC-HPLC.
  • Immobilized Human 4-1BB Ligand (Trimer) , His Tag at 1 Mu g/ml (100 Mu l/Well) on the plate. Dose response curve for Biotinylated Human 4-1BB, hFc Tag with the EC50 of 38. 2ng/ml determined by ELISA.

Human 4-1BB/TNFRSF9 protein (Recombinant) (C-hFc-Avi) {Biotin} (STJP001627)

SKU:
STJP001627

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Host: HEK293
Note: STRICTLY FOR FURTHER RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Recombinant-Human 4-1BB/TNFRSF9-C-hFc-Avi protein was developed from hek293 and has a target region of C-hFc-Avi. For use in research applications.
Conjugation: Biotin
Formulation: Lyophilised from 0.2 µm filtered PBS solution pH7.4.
Dilution Range: Upon receipt centrifuge vial to ensure maximal product extraction, recommended: 20sec, 5K RPM
Storage Instruction: The lyophilized protein is stable for at least 1 year from date of receipt at-20°C.
Endotoxin: Endotoxin content was assayed using a LAL gel clot method. Endotoxin level was found to be less than 0.1 ng/µg (1EU/µg).
Gene Symbol: TNFRSF9
Gene ID: 3604
Uniprot ID: TNR9_HUMAN
Immunogen Region: Leu24-Gln186
Immunogen: DNA sequence encoding Human 4-1BB/TNFRSF9 including a C-hFc-Avi tag was expressed in HEK293 Cells. The recombinant protein was then biotinylated site specific using the AVItag biotinylation technology.
Function Receptor for TNFSF9/4-1BBL. Conveys a signal that enhances CD8(+) T-cell survival, cytotoxicity, and mitochondrial activity, thereby promoting immunity against viruses and tumors (Probable).
Protein Name Tumor Necrosis Factor Receptor Superfamily Member 9
4-1bb Ligand Receptor
Cdw137
T-Cell Antigen 4-1bb Homolog
T-Cell Antigen Ila
Cd Antigen Cd137
Database Links Reactome: R-HSA-5669034
Cellular Localisation Cell Membrane
Single-Pass Type I Membrane Protein
Alternative Protein Names Tumor Necrosis Factor Receptor Superfamily Member 9 protein
4-1bb Ligand Receptor protein
Cdw137 protein
T-Cell Antigen 4-1bb Homolog protein
T-Cell Antigen Ila protein
Cd Antigen Cd137 protein
TNFRSF9 protein
CD137 protein
ILA protein

Information sourced from Uniprot.org

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