Human 17 beta-HSD14/HSD17B14 protein (Recombinant) (His-Tag) (STJP016937)
SPECIFICATIONS
HostE.coli
ImmunogenHuman
General Information
| Short Description | Recombinant-Human 17 beta-HSD14/HSD17B14-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications. |
| Applications | SDS-PAGE |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Concentration | 1 mg/mL |
| Formulation | Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 20% Glycerol, 0.1M NaCl, 1mM DTT |
| Storage Instruction | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | HSD17B14 |
| Gene ID | 51171 |
| Uniprot ID | DHB14_HUMAN |
| Accession Number | NP_057330 |
| Immunogen | Human |
| Immunogen Region | 1-270aa |
| Immunogen Sequence |
Additional Info
| Tissue Specificity | Highly expressed in brain, placenta, liver and kidney. |
| Function | Catalyzes the NAD(+)-dependent oxidation of L-fucose, yielding L-fucono-1,5-lactone, which rapidly converts spontaneously to L-fucone-1,4-lactone. Can also act on D-arabinose and L-galactose, with lower catalytic efficiency. Does not use NADPH. May be the initial enzyme of the L-fucose degradation pathway in mammals. |
| Protein Name | L-Fucose Dehydrogenase17-Beta-Hydroxysteroid Dehydrogenase Dhrs10Dehydrogenase/Reductase Sdr Family Member 10Retinal Short-Chain Dehydrogenase/Reductase Retsdr3Short Chain Dehydrogenase/Reductase Family 47c Member 1 |
| Database Links | Reactome: R-HSA-193144 |
| Cellular Localisation | Cytoplasm |
| Alternative Protein Names | L-Fucose Dehydrogenase protein17-Beta-Hydroxysteroid Dehydrogenase Dhrs10 proteinDehydrogenase/Reductase Sdr Family Member 10 proteinRetinal Short-Chain Dehydrogenase/Reductase Retsdr3 proteinShort Chain Dehydrogenase/Reductase Family 47c Member 1 proteinHSD17B14 proteinDHRS10 proteinSDR3 proteinSDR47C1 proteinUNQ502 proteinPRO474 protein |
Information sourced from Uniprot.org