Human 17 beta-HSD1/HSD17B1 protein (Recombinant) (His-Tag) (STJP018208)

Name: Human 17 beta-HSD1/HSD17B1 protein (Recombinant) (His-Tag) (STJP018208)
SKU: STJP018208
Availability: InStock

⇓ Datasheet ⇓ SDS

SPECIFICATIONS

HostE.coli

ImmunogenHuman

STJP018208

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Short Description	Recombinant-Human 17 beta-HSD1/HSD17B1-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications.
Applications	SDS-PAGE
Host	E.coli
Note	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Concentration	1 mg/mL
Formulation	Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 10% Glycerol, 1mM DTT
Storage Instruction	For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles.

Gene Symbol	HSD17B1
Gene ID	3292
Uniprot ID	DHB1_HUMAN
Accession Number	NP_000404
Immunogen	Human
Immunogen Region	1-328aa
Immunogen Sequence	MARTVV LITGCSSGIG LHLAVRLASD PSQSFKVYAT LRDLKTQGRL WEAARALACP PGSLETLQLD VRDSKSVAAA RERVTEGRVD VLVCNAGLGL LGPLEALGED AVASVLDVNV VGTVRMLQAF LPDMKRRGSG RVLVTGSVGG LMGLPFNDVY CASKFALEGL CESLAVLLLP FGVHLSLIEC GPVHTAFMEK VLGSPE

Function	Favors the reduction of estrogens and androgens. Converts estrone (E1) to a more potent estrogen, 17beta-estradiol (E2). Also has 20-alpha-HSD activity. Uses preferentially NADH.
Protein Name	17-Beta-Hydroxysteroid Dehydrogenase Type 1 17-Beta-Hsd 1 20 Alpha-Hydroxysteroid Dehydrogenase 20-Alpha-Hsd E2dh Estradiol 17-Beta-Dehydrogenase 1 Placental 17-Beta-Hydroxysteroid Dehydrogenase Short Chain Dehydrogenase/Reductase Family 28c Member 1
Database Links	Reactome: R-HSA-193144 Reactome: R-HSA-2453902
Cellular Localisation	Cytoplasm
Alternative Protein Names	17-Beta-Hydroxysteroid Dehydrogenase Type 1 protein 17-Beta-Hsd 1 protein 20 Alpha-Hydroxysteroid Dehydrogenase protein 20-Alpha-Hsd protein E2dh protein Estradiol 17-Beta-Dehydrogenase 1 protein Placental 17-Beta-Hydroxysteroid Dehydrogenase protein Short Chain Dehydrogenase/Reductase Family 28c Member 1 protein HSD17B1 protein E17KSR protein EDH17B1 protein EDH17B2 protein EDHB17 protein SDR28C1 protein

Information sourced from Uniprot.org