Histone H3 Blocking Peptide peptide (STJ504221)
SPECIFICATIONS
ImmunogenSynthetic peptide taken within amino acid 1-50 on Sacchoromyces cerevisiae protein HH3 protein.
General Information
| Short Description | Histone H3 Blocking Peptide is synthetically produced from the 1-50 aa sequence and is suitable for use in western blot applications. |
| Applications | Immunodepletion/Immunocompetition |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Formulation | Liquid form at 2.5mg/ml concentration in PBS. Up to 5% DMSO can be added. Orders with >1mg can be supplied in lyophilized powder form, or in buffer of choice. |
| Storage Instruction | Store at-20ยฐC for long term storage. Avoid freeze-thaw cycles. |
Target Information
| Immunogen | Synthetic peptide taken within amino acid 1-50 on Sacchoromyces cerevisiae protein HH3 protein. |
| Immunogen Region | 1-50 aa |
Additional Info
| Background | Histone methyltransferase that specifically methylates histone H3 to form H3K79me. This methylation is required for telomere silencing and for the pachytene checkpoint during the meiotic cell cycle by allowing the recruitment of RAD9 to double strand breaks. Nucleosomes are preferred as substrate compared to free histones. Can bind to DNA (in vitro). |
Information sourced from Uniprot.org