HAND2 Blocking Peptide is synthetically produced from the sequence and is suitable for use in western blot applications.
Applications
Immunodepletion/Immunocompetition
Note
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Product Properties
Formulation
Liquid form at 2.5mg/ml concentration in PBS. Up to 5% DMSO can be added. Orders with >1mg can be supplied in lyophilized powder form, or in buffer of choice.
Storage Instruction
Store at-20ยฐC for long term storage. Avoid freeze-thaw cycles.
Synthetic peptide corresponding to unique amino acid sequences on Heart and neuronal crest derivative protein 2.
Additional Info
Function
Essential for cardiac morphogenesis, particularly for the formation of the right ventricle and of the aortic arch arteries. Required for vascular development and regulation of angiogenesis, possibly through a VEGF signaling pathway. Also plays an important role in limb development, particularly in the establishment of anterior-posterior polarization, acting as an upstream regulator of sonic hedgehog (SHH) induction in the limb bud. Is involved in the development of branchial arches, which give rise to unique structures in the head and neck. Binds DNA on E-box consensus sequence 5'-CANNTG-3'.
Peptide Name
Heart- And Neural Crest Derivatives-Expressed Protein 2Deciduum - Heart - Autonomic Nervous System And Neural Crest Derivatives-Expressed Protein 2Dhand
Cellular Localisation
Nucleus
Alternative Peptide Names
Heart- And Neural Crest Derivatives-Expressed Protein 2 proteinDeciduum - Heart - Autonomic Nervous System And Neural Crest Derivatives-Expressed Protein 2 proteinDhand proteinHand2 proteinDhand protein
