GPCR GPR7 Positive Control peptide (STJ505406)

SPECIFICATIONS
STJ505406-5
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General Information

Short DescriptionGPCR GPR7 Positive Control is synthetically produced from the sequence and is suitable for use in western blot applications.
ApplicationsWB
NoteSTRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Product Properties

Dilution RangeWB: 1:500
FormulationProvided as 100 uL ready-to-use, in SDS-PAGE sample buffer (Laemelli's buffer) containing Tris, pH 6.8, 1 % SDS, Glycerol and Bromophenolblue blue as tracking dye. The sample is reduced by adding 2% beta mercaptoethanol. The protein concentration is
Storage InstructionStore at-20°C for long term storage. Avoid freeze-thaw cycles.

Target Information

Gene SymbolNPBWR1
Gene ID2831
Uniprot IDNPBW1_HUMAN

Additional Info

Tissue Specificity Found in cerebellum and frontal cortex. Detected at high levels in hippocampus, amygdala and trachea.at moderate levels in fetal brain, pituitary gland and prostate. Not in caudate, accumbens, kidney or liver. Also detected at high levels in lung carcinoma.
Function Interacts specifically with a number of opioid ligands. Receptor for neuropeptides B and W, which may be involved in neuroendocrine system regulation, food intake and the organization of other signals. Has a higher affinity for neuropeptide B.
Peptide Name Neuropeptides B/W Receptor Type 1
G-Protein Coupled Receptor 7
Database Links Reactome: R-HSA-375276
Reactome: R-HSA-418594
Cellular Localisation Cell Membrane
Multi-Pass Membrane Protein
Alternative Peptide Names Neuropeptides B/W Receptor Type 1 protein
G-Protein Coupled Receptor 7 protein
NPBWR1 protein
GPR7 protein

Information sourced from Uniprot.org

Citations

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