Glucose Transporter GLUT2 Blocking Peptide is synthetically produced from the 1-60 sequence and is suitable for use in western blot applications.
Applications
Immunodepletion/Immunocompetition
Note
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Product Properties
Formulation
Liquid form at 2.5mg/ml concentration in PBS. Up to 5% DMSO can be added. Orders with >1mg can be supplied in lyophilized powder form, or in buffer of choice.
Storage Instruction
Store at-20°C for long term storage. Avoid freeze-thaw cycles.
Synthetic peptide taken within amino acid region 1-50 on human GLUT2 protein.
Immunogen Region
1-60
Additional Info
Tissue Specificity
In embryo, expressed in endoderm layer of yolk sac and liver primordium.
Post Translational Modifications
N-glycosylated.required for stability and retention at the cell surface of pancreatic beta cells.
Function
Facilitative hexose transporter that mediates the transport of glucose, fructose and galactose. Likely mediates the bidirectional transfer of glucose across the plasma membrane of hepatocytes and is responsible for uptake of glucose by the beta cells.may comprise part of the glucose-sensing mechanism of the beta cell. May also participate with the Na(+)/glucose cotransporter in the transcellular transport of glucose in the small intestine and kidney. Also able to mediate the transport of dehydroascorbate.
Peptide Name
Solute Carrier Family 2 - Facilitated Glucose Transporter Member 2Glucose Transporter Type 2 - LiverGlut-2
Solute Carrier Family 2 - Facilitated Glucose Transporter Member 2 proteinGlucose Transporter Type 2 - Liver proteinGlut-2 proteinSlc2a2 proteinGlut2 protein
